Cyclazocine
Cyclazocine is a μ, δ, and κ opioid receptor modulator with Ki values of 0.32, 1.1, and 0.18 nM, respectively. Cyclazocine exhibits "mixed" pharmacological activities, acting as a μ-partial antagonist, κ-agonist, and low-affinity δ ligand. Cyclazocine shows antinociceptive activity in mice. Cyclazocine can be used in studies on psychoactive substance addiction.
For research use only. We do not sell to patients.
- CAS No.: 3572-80-3
- Formula: C18H25NO
- Molecular Weight:271.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
All Opioid Receptor Isoforms
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Biological Activity
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μ Opioid Receptor/MOR 0.32 nM (Ki) |
κ Opioid Receptor/KOR 1.1 nM (Ki) |
δ Opioid Receptor/DOR 0.18 nM (Ki) |
Cyclazocine potently binds to μ, δ, and κ opioid receptors in guinea pig brain cell membranes, with Ki values of 0.32 nM, 1.1 nM, and 0.18 nM, respectively[1].
Cyclazocine potently binds to the human μ-opioid receptor stably expressed in CHO cells, with a Ki value of 0.16 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3572-80-3
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Molecular Weight 271.40
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Formula C18H25NO
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SMILES
OC1=CC=C2C(C3(CCN(C(C3C)C2)CC4CC4)C)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cyclazocine Related Classifications
HY-125790 Related Classifications
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