1. Metabolic Enzyme/Protease
  2. Glyoxalase (GLO)
  3. N,S-Bis-Fmoc-Glutathione TFA

N,S-Bis-Fmoc-Glutathione TFA is a potent glyoxalase II inhibitor with a Ki value of 0.75 μM and an IC50 of 2.5 μM.

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N,S-Bis-Fmoc-Glutathione TFA

N,S-Bis-Fmoc-Glutathione TFA Chemical Structure

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25 mg En stock
50 mg En stock
100 mg En stock
200 mg   Obtenir un devis  
500 mg   Obtenir un devis  

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Description

N,S-Bis-Fmoc-Glutathione TFA is a potent glyoxalase II inhibitor with a Ki value of 0.75 μM and an IC50 of 2.5 μM[1].

Masse moléculaire

865.82

Formule

C42H38F3N3O12S

Appearance

Solid

Sequence

{Fmoc}-{γ-Glu(({Cys-Fmoc})-Gly)}

Sequence Shortening

{Fmoc}-{γ-Glu(({Cys-Fmoc})-Gly)}

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvant et solubilité
In Vitro: 

DMSO : 50 mg/mL (57.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1550 mL 5.7749 mL 11.5497 mL
5 mM 0.2310 mL 1.1550 mL 2.3099 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculateur de molarité

  • Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureté et documentation
Références

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1550 mL 5.7749 mL 11.5497 mL 28.8744 mL
5 mM 0.2310 mL 1.1550 mL 2.3099 mL 5.7749 mL
10 mM 0.1155 mL 0.5775 mL 1.1550 mL 2.8874 mL
15 mM 0.0770 mL 0.3850 mL 0.7700 mL 1.9250 mL
20 mM 0.0577 mL 0.2887 mL 0.5775 mL 1.4437 mL
25 mM 0.0462 mL 0.2310 mL 0.4620 mL 1.1550 mL
30 mM 0.0385 mL 0.1925 mL 0.3850 mL 0.9625 mL
40 mM 0.0289 mL 0.1444 mL 0.2887 mL 0.7219 mL
50 mM 0.0231 mL 0.1155 mL 0.2310 mL 0.5775 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nom du produit:
N,S-Bis-Fmoc-Glutathione TFA
Cat. No.:
HY-P4277A
Quantité:
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