Ostarine-d₄  (Synonyms: MK-2866-d₄; GTX-024-d₄; Enobosarm-d₄)

Ostarine-d4 is a deuterated labeled Ostarine^[1].

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

393.35

C₁₉H₁₀D₄F₃N₃O₃

1202044-20-9

841205-47-8

Solid

White to off-white

FC(F)(C1=C(C=CC(NC([C@@](C)(O)COC2=C([2H])C([2H])=C(C([2H])=C2[2H])C#N)=O)=C1)C#N)F

Room temperature in continental US; may vary elsewhere.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Thevis M, et al. Trafficking of drug candidates relevant for sports drug testing: detection of non-approved therapeutics categorized as anabolic and gene doping agents in products distributed via the Internet. Drug Test Anal. 2011 May;3(5):331-6. doi: 10.1002/dta.283.  [Content Brief]

  [3]. Zilbermint MF, et al. Nonsteroidal selective androgen receptor modulator Ostarine in cancer cachexia. Nonsteroidal selective androgen receptor modulator Ostarine in cancer cachexia.