1. GPCR/G Protein
  2. Protease Activated Receptor (PAR)
  3. PAR 4 (1-6) TFA

PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide, is a fragment of protease-activated receptor 4 (PAR4). PAR 4 (1-6) TFA acts as a PAR4-specific agonist.

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PAR 4 (1-6) TFA

PAR 4 (1-6) TFA Estructura química

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Descripciòn

PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide, is a fragment of protease-activated receptor 4 (PAR4). PAR 4 (1-6) TFA acts as a PAR4-specific agonist[1].

IC50 & Target

PAR4[1]

In Vitro

PAR 4 (1-6) (GYPGQV) stimulats [3H]-thymidine incorporation in SMC. At 500 μM, the peptide increases DNA synthesis 2.5 fold above controls. A comparable mitogenic effect is obtained after stimulation of the SMC by 10 nM thrombin or 100 μM SFLLRN, respectively[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fòrmula

C28H41N7O9.xC2HF3O2

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Room temperature in continental US; may vary elsewhere.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
PAR 4 (1-6) TFA
Cat. No.:
HY-P1313A
Cantidad:
MCE Japan Authorized Agent: