1. Anti-infection
  2. Fungal
  3. PF-184563

Janthitrem F is a metabolite isolated from tremorigen-producing Penicillium and a potential causative agent of ryegrass spurt disease.

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PF-184563

PF-184563 構造式

CAS 番号 : 748806-39-5

容量 価格(税別) 在庫状況 数量
1 mg $888 お問い合わせ 2 - 3 weeks 1-2 weeks 3 - 4 weeks 2-3 weeks
5 mg $2059 お問い合わせ 2 - 3 weeks 1-2 weeks 3 - 4 weeks 2-3 weeks
10 mg $2714 お問い合わせ 2 - 3 weeks 1-2 weeks 3 - 4 weeks 2-3 weeks
25 mg $4125 お問い合わせ 2 - 3 weeks 1-2 weeks 3 - 4 weeks 2-3 weeks
50 mg $5445 お問い合わせ 2 - 3 weeks 1-2 weeks 3 - 4 weeks 2-3 weeks
100 mg   お問い合わせ  
200 mg   お問い合わせ  
Synthetic products have potential research and development risk.

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This product is a controlled substance and not for sale in your territory.

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製品説明

Janthitrem F is a metabolite isolated from tremorigen-producing Penicillium and a potential causative agent of ryegrass spurt disease.

IC50 & Target

Penicillium sp.[1]

Cellular Effect
Cell Line Type Value Description References
CHO IC50
6.7 nM
Compound: 13d, PF-184563
Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds by FLIPR assay
Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds by FLIPR assay
[PMID: 21885275]
HEK293 IC50
17900 nM
Compound: 13d, PF-184563
Displacement of [3H]dofetilide from human ERG transfected in HEK293 cells by fluorescence polarization binding assay
Displacement of [3H]dofetilide from human ERG transfected in HEK293 cells by fluorescence polarization binding assay
[PMID: 21885275]
分子量

394.90

分子式

C21H23ClN6

CAS 番号
SMILES

CN1CC2=CC(Cl)=CC=C2N3C(C4CCN(CC4)C5=NC=CC=C5)=NN=C3C1

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション
参考文献
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PF-184563 Related Classifications

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一般には略語で表示されます:C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

製品名:
PF-184563
製品番号:
HY-121163
数量:
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