2. JAK/STAT Signaling
  3. Pim
  4. Pim-1 kinase inhibitor 5

Pim-1 kinase inhibitor 5 (Compound 4c) is a Pim-1 kinase inhibitor (IC50: 0.61 μM). Pim-1 kinase inhibitor 5 shows cytotoxicity against cancer cells, with IC50s of 6.95-20.19 μM for HepG2, MCF-7, PC3, and HCT-116 cells.

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Pim-1 kinase inhibitor 5

Pim-1 kinase inhibitor 5 Chemische Struktur

CAS. Nr. : 2928606-67-9

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Beschreibung

Pim-1 kinase inhibitor 5 (Compound 4c) is a Pim-1 kinase inhibitor (IC50: 0.61 μM). Pim-1 kinase inhibitor 5 shows cytotoxicity against cancer cells, with IC50s of 6.95-20.19 μM for HepG2, MCF-7, PC3, and HCT-116 cells[1].

Molekulargewicht

406.26

Formel

C22H13Cl2N3O
CAS. Nr.
SMILES

ClC(C(C1=CC(C2=CC=C(OC)C=C2)=NC(Cl)=C1C#N)=C3)=NC4=C3C=CC=C4
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Room temperature in continental US; may vary elsewhere.
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Pim-1 kinase inhibitor 5 Related Classifications

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Keywords:

Pim-1 kinase inhibitor 52928606-67-9PimPim kinasesAnti-cancerHepG2MCF-7PC3HCT-116Inhibitorinhibitorinhibit

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