2928606-67-9
2928606-67-9
Chemical Structure
Pim-1 kinase inhibitor 5
- CAS No.: 2928606-67-9
- Formula:C22H13Cl2N3O
- Molecular Weight:406.26
InChIKey: JTCXKTJMNJNUGG-UHFFFAOYSA-N
SMILES: ClC(C(C1=CC(C2=CC=C(OC)C=C2)=NC(Cl)=C1C#N)=C3)=NC4=C3C=CC=C4
Biological Activity: Pim-1 kinase inhibitor 5 (Compound 4c) is a Pim-1 kinase inhibitor (IC50: 0.61 μM). Pim-1 kinase inhibitor 5 shows cytotoxicity against cancer cells, with IC50s of 6.95-20.19 μM for HepG2, MCF-7, PC3, and HCT-116 cells[1].
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Pim-1 kinase inhibitor 5 | Pim-1 kinase inhibitor 5 (Compound 4c) is a Pim-1 kinase inhibitor (IC50: 0.61 μM). Pim-1 kinase inhibitor 5 shows cytotoxicity against cancer cells, with IC50s of 6.95-20.19 μM for HepG2, MCF-7, PC3, and HCT-116 cells. | |||||||||||||||||||||
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