2. JAK/STAT Signaling
  3. Pim
  4. PIM1-IN-7

PIM1-IN-7 (compound 6c) is a potent PIM-1 inhibitor, with an IC50 of 0.67 μM. PIM1-IN-7 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 42.9 and 7.68 μM, respectively.

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PIM1-IN-7

PIM1-IN-7 Estructura química

No. CAS : 2439168-72-4

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PIM1-IN-7 Related Antibodies

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Descripciòn

PIM1-IN-7 (compound 6c) is a potent PIM-1 inhibitor, with an IC50 of 0.67 μM. PIM1-IN-7 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 42.9 and 7.68 μM, respectively[1].

IC50 & Target

PIM1

0.67 μM (IC50)

Peso molecular

385.46

Fòrmula

C23H23N5O
No. CAS
SMILES

O=C(C1=C2N=C(C)C=C(C)N2N=C1NC3=CC=CC=C3)NC4=C(C)C=CC=C4C
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

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Pureza y Documentación
Referencias
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PIM1-IN-7 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PIM1-IN-72439168-72-4PimPim kinasesPyrazolo[1,5-a]pyrimidineAntitumor activityHCT-116MCF-7Inhibitorinhibitorinhibit

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Nombre del producto:
PIM1-IN-7
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