2439168-72-4
2439168-72-4
Chemical Structure
PIM1-IN-7
- CAS No.: 2439168-72-4
- Formula:C23H23N5O
- Molecular Weight:385.46
IUPAC Name: N-(2,6-dimethylphenyl)-5,7-dimethyl-2-(phenylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
InChIKey: BESUIJNZKPSODK-UHFFFAOYSA-N
SMILES: O=C(C1=C2N=C(C)C=C(C)N2N=C1NC3=CC=CC=C3)NC4=C(C)C=CC=C4C
Biological Activity: PIM1-IN-7 (compound 6c) is a potent PIM-1 inhibitor, with an IC50 of 0.67 μM. PIM1-IN-7 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 42.9 and 7.68 μM, respectively[1].
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PIM1-IN-7 | PIM1-IN-7 (compound 6c) is a potent PIM-1 inhibitor, with an IC50 of 0.67 μM. PIM1-IN-7 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 42.9 and 7.68 μM, respectively. | |||||||||||||||||||||
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References
Keywords
