2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species (ROS)
  4. Pirenoxine

Pirenoxine (Catalin K) is a potent antioxidant. Pirenoxine shows anti-presbyopic activity. Pirenoxine has the potential for the research of cataracts.

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Pirenoxine

Pirenoxine Chemische Struktur

CAS. Nr. : 1043-21-6

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Beschreibung

Pirenoxine (Catalin K) is a potent antioxidant. Pirenoxine shows anti-presbyopic activity. Pirenoxine has the potential for the research of cataracts[1][2].

In Vivo

Pirenoxine (0.005% pirenoxine; eye drop) suppresses lens hardening and prevents the progression of presbyopia[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Six-week-old male Sprague-Dawley rats[2]
Dosage: 0.005% pirenoxine
Administration: Eye drop
Result: Significantly suppressed lens hardening.
Molekulargewicht

308.25

Formel

C16H8N2O5
CAS. Nr.
Appearance

Solid

Color

Light brown to brown

SMILES

O=C(C1=CC(O)=C2C(C(C=C3OC4=C(N=C32)C=CC=C4)=O)=N1)O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro: 

H2O : < 0.1 mg/mL (insoluble)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pirenoxine1043-21-6Catalin KReactive Oxygen Species (ROS)Inhibitorinhibitorinhibit

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