1043-21-6
1043-21-6
Chemical Structure
Pirenoxine
Synonym(s): Catalin K
- CAS No.: 1043-21-6
- Formula:C16H8N2O5
- Molecular Weight:308.25
IUPAC Name: 1-hydroxy-5-oxo-5H-pyrido[3,2-a]phenoxazine-3-carboxylic acid
InChIKey: OKPNYGAWTYOBFZ-UHFFFAOYSA-N
SMILES: O=C(C1=CC(O)=C2C(C(C=C3OC4=C(N=C32)C=CC=C4)=O)=N1)O
Biological Activity: Pirenoxine (Catalin K) is an antioxidant with lens-protective activity. Pirenoxine inhibits lens sclerosis, prevents lipid peroxidation and suppresses lens protein opacification. Pirenoxine blocks benzoquinone acetic acid-induced cataract progression. Pirenoxine can be used in research related to presbyopia and cataracts[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pirenoxine | 95.0% | Pirenoxine (Catalin K) is an antioxidant with lens-protective activity. Pirenoxine inhibits lens sclerosis, prevents lipid peroxidation and suppresses lens protein opacification. Pirenoxine blocks benzoquinone acetic acid-induced cataract progression. Pirenoxine can be used in research related to presbyopia and cataracts. | ||||||||||||||||||||
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References
- [1]. Tsuneyoshi Y, et al. Suppression of presbyopia progression with pirenoxine eye drops: experiments on rats and non-blinded, randomized clinical trial of efficacy. Scientific reports. 2017 Jul 28;7(1):6819. [Content Brief]
- [2]. Upaphong P, et al. The Possible Positive Mechanisms of Pirenoxine in Cataract Formation. International journal of molecular sciences. 2022 Aug 21;23(16):9431. [Content Brief]
