2. Disease Areas
  3. Neurological, Eye or Ear Disease
  4. Visual System Disease
  5. Cataract

Cataract

Cataract is characterized by opacification of the eye's lens, which may be present at birth, develop early in life, or result from trauma. It is the leading cause of blindness worldwide and is frequently associated with aging, resulting in vision impairment that can be effectively treated through surgical intervention.

References:

Cataract (3):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-151231
    6-Hydroxyluteolin 18003-33-3 99.02%
    6-Hydroxyluteolin (Compound 17) is a flavonoid derivative and also an inhibitor of Aldose reductase, with an experimental -log IC50 value of 6.690. 6-Hydroxyluteolin can be isolated from the leaves of multiple plant families, including Plantaginaceae, Globulariaceae and Labiatae. 6-Hydroxyluteolin serves as a phylogenetic marker for higher plants. 6-Hydroxyluteolin can be used in the research of diabetic cataract.
    6-Hydroxyluteolin
  • HY-B1087
    Prednisolone hemisuccinate 2920-86-7 99.89%
    Prednisolone hemisuccinate (Prednisolone 21-hemisuccinate) is a prodrug of Prednisolone (HY-17463) and a glucocorticoid. Prednisolone hemisuccinate converts to Prednisolone in vivo. Prednisolone hemisuccinate induces the inactivation of glyceraldehyde-3-phosphate dehydrogenase (GAP-DH) in vitro. Prednisolone hemisuccinate can be used in research related to cataracts.
    Prednisolone hemisuccinate
  • HY-113033
    Pentosidine 124505-87-9
    Pentosidine is a fluorescent advanced glycation end product (AGE) and cross-linker. Pentosidine is a fluorescent cross-linked structure formed by lysine and arginine in sugar oxidation reactions, and it is commonly found in collagen, skin, bone, lens and plasma proteins. Pentosidine is used in research related to type 1 diabetes, brown cataracts, rheumatoid arthritis, atherosclerosis and neurodegenerative diseases.
    Pentosidine