6-Hydroxyluteolin

Cat. No.: HY-151231 Purity: 99.02%: Data Sheet
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6-Hydroxyluteolin (Compound 17) is a flavonoid derivative and also an inhibitor of Aldose reductase, with an experimental -log IC₅₀ value of 6.690. 6-Hydroxyluteolin can be isolated from the leaves of multiple plant families, including Plantaginaceae, Globulariaceae and Labiatae. 6-Hydroxyluteolin serves as a phylogenetic marker for higher plants. 6-Hydroxyluteolin can be used in the research of diabetic cataract.

For research use only. We do not sell to patients.

6-Hydroxyluteolin Chemical Structure

CAS No. : 18003-33-3

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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Description

In Vitro

6-Hydroxyluteolin inhibits rat lens aldose reductase, with an experimental -log IC₅₀ value of 6.690^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

302.24

Formula

C₁₅H₁₀O₇

CAS No.

18003-33-3

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=C(O)C(O)=C13

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

Methanol : 4 mg/mL (13.23 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3086 mL	16.5431 mL	33.0863 mL
5 mM	0.6617 mL	3.3086 mL	6.6173 mL
10 mM	0.3309 mL	1.6543 mL	3.3086 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Purity & Documentation

Purity: 99.02%

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Data Sheet (272 KB) SDS (393 KB)

COA (249 KB)

Handling Instructions (2659 KB)

References

[1]. Harborne J B, et al. 6-Hydroxyluteolin and scutellarein as phyletic markers in higher plants[J]. Phytochemistry, 1971, 10(2): 367-378.

[2]. Mercader AG, et al. QSAR prediction of inhibition of aldose reductase for flavonoids. Bioorg Med Chem. 2008;16(15):7470-7476. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Methanol	1 mM	3.3086 mL	16.5431 mL	33.0863 mL	82.7157 mL
	5 mM	0.6617 mL	3.3086 mL	6.6173 mL	16.5431 mL
	10 mM	0.3309 mL	1.6543 mL	3.3086 mL	8.2716 mL