2. NF-κB
  3. NF-κB
  4. OT-551

OT-551 is a NF-κB inhibitor with antioxidant and anti-inflammatory effects. OT-551 has the potential for retinal diseases research.

For research use only. We do not sell to patients.

OT-551 Chemical Structure

OT-551 Chemical Structure

CAS No. : 627085-15-8

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Description

OT-551 is a NF-κB inhibitor with antioxidant and anti-inflammatory effects. OT-551 has the potential for retinal diseases research[1][2].

In Vivo

OT-551 (25-100 mg/kg; ip; once) provides RPE cell protection against acute light damage in albino rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley (SD) albino rats (6-7 weeks of age) exposure to 2700 lux white fluorescent light[1]
Dosage: 25, 50, or 100 mg/kg
Administration: ip; once
Result: Retinal pigment epithelium (RPE) damage index was significantly lower in the animals.
Molecular Weight

277.79

Formula

C13H24ClNO3
CAS No.
Unlabeled CAS

SMILES

CC1(C)CC(OC(C2CC2)=O)CC(C)(C)N1O.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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OT-551 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

OT-551627085-15-8OT551OT 551NF-κBNuclear factor-κBNuclear factor-kappaBNF-κB inhibitorantioxidantanti-inflammatory effectsretinal diseasesInhibitorinhibitorinhibit

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