51410-30-1
Chemical Structure
Pirenoxine sodium
Synonym(s): Catalin K sodium
- CAS No.: 51410-30-1
- Formula:C16H7N2NaO5
- Molecular Weight:330.23
IUPAC Name: 1-hydroxy-5-oxo-5H-pyrido[3,2-a]phenoxazine-3-carboxylic acid, sodium salt
InChIKey: HDQXPMXHXZNPKE-UHFFFAOYSA-M
SMILES: O=C(C(N=C12)=CC(O)=C2C3=NC4=C(C=CC=C4)OC3=CC1=O)O[Na]
Biological Activity: Pirenoxine sodium (Catalin K sodium) is an antioxidant with lens-protective activity. Pirenoxine sodium inhibits lens sclerosis, prevents lipid peroxidation and suppresses lens protein opacification. Pirenoxine sodium blocks benzoquinone acetic acid-induced cataract progression. Pirenoxine sodium can be used in research related to presbyopia and cataracts[1][2].
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Pirenoxine sodium | Pirenoxine sodium (Catalin K sodium) is an antioxidant with lens-protective activity. Pirenoxine sodium inhibits lens sclerosis, prevents lipid peroxidation and suppresses lens protein opacification. Pirenoxine sodium blocks benzoquinone acetic acid-induced cataract progression. Pirenoxine sodium can be used in research related to presbyopia and cataracts. | |||||||||||||||||||||
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- [1]. Tsuneyoshi Y, et al. Suppression of presbyopia progression with pirenoxine eye drops: experiments on rats and non-blinded, randomized clinical trial of efficacy. Scientific reports. 2017 Jul 28;7(1):6819. [Content Brief]
- [2]. Upaphong P, et al. The Possible Positive Mechanisms of Pirenoxine in Cataract Formation. International journal of molecular sciences. 2022 Aug 21;23(16):9431. [Content Brief]
Keywords
