1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. N-Acetyl-L-histidine monohydrate

N-Acetyl-L-histidine monohydrate 

Cat. No.: HY-W014180 Purity: >97.0%
Handling Instructions

N-Acetyl-L-histidine monohydrate, a histidine derivative, is a prominent biomolecule in brain, retina and lens of poikilothermic vertebrates. N-Acetyl-L-histidine monohydrate has a role as an animal metabolite.

For research use only. We do not sell to patients.

N-Acetyl-L-histidine monohydrate Chemical Structure

N-Acetyl-L-histidine monohydrate Chemical Structure

CAS No. : 39145-52-3

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500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

N-Acetyl-L-histidine monohydrate, a histidine derivative, is a prominent biomolecule in brain, retina and lens of poikilothermic vertebrates. N-Acetyl-L-histidine monohydrate has a role as an animal metabolite[1].

In Vitro

N-Acetyl-L-histidine monohydrate (NAH) also exhibits a strong phylogenetic component in that it is a major osmolyte in the brain and eye of teleost (bony) fish, amphibians and reptiles, but is present in much lower amounts in brain and other tissues of homeothermic (endothermic) vertebrates[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

215.21

Formula

C₈H₁₃N₃O₄

CAS No.

39145-52-3

SMILES

O=C(O)[[email protected]](CC1=CNC=N1)NC(C)=O.[H]O[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (464.66 mM; Need ultrasonic)

DMSO : 20 mg/mL (92.93 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6466 mL 23.2331 mL 46.4662 mL
5 mM 0.9293 mL 4.6466 mL 9.2932 mL
10 mM 0.4647 mL 2.3233 mL 4.6466 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2 mg/mL (9.29 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2 mg/mL (9.29 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2 mg/mL (9.29 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

N-Acetyl-L-histidineEndogenous MetabolitehistidinederivativeprominentbiomoleculemetaboliteInhibitorinhibitorinhibit

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Product Name:
N-Acetyl-L-histidine monohydrate
Cat. No.:
HY-W014180
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