7659-29-2
7659-29-2
Chemical Structure
3,5-Dinitrocatechol
Synonym(s): OR-486; 3,5-Dinitropyrocatechol
- CAS No.: 7659-29-2
- Formula:C6H4N2O6
- Molecular Weight:200.11
IUPAC Name: 3,5-dinitrobenzene-1,2-diol
InChIKey: VDCDWNDTNSWDFJ-UHFFFAOYSA-N
SMILES: OC1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1O
Biological Activity: 3,5-Dinitrocatechol (OR-486) is a potent catechol-O-methyltransferase inhibitor, with an IC50 of 12 nM. 3,5-Dinitrocatechol can be used in the preparation of the molybdenum (VI)- 3,5-Dinitrocatechol complex[1][2][3].
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3,5-Dinitrocatechol | 99.72% | 3,5-Dinitrocatechol (OR-486) is a potent catechol-O-methyltransferase inhibitor, with an IC50 of 12 nM. 3,5-Dinitrocatechol can be used in the preparation of the molybdenum (VI)- 3,5-Dinitrocatechol complex. | ||||||||||||||||||||
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3,5-Dinitrocatechol (Standard) | ≥98% | 3,5-Dinitrocatechol (Standard) is the analytical standard of 3,5-Dinitrocatechol. This product is intended for research and analytical applications. 3,5-Dinitrocatechol (OR-486) is a potent catechol-O-methyltransferase inhibitor, with an IC50 of 12 nM. 3,5-Dinitrocatechol can be used in the preparation of the molybdenum (VI)- 3,5-Dinitrocatechol complex. | ||||||||||||||||||||
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References
- [1]. Nissinen E, et, al. Inhibition of catechol-O-methyltransferase activity by two novel disubstituted catechols in the rat. Eur J Pharmacol. 1988 Aug 24;153(2-3):263-9. [Content Brief]
- [2]. Yamaki F, et, al. Effects of Catecholamine Metabolites on Beta-Adrenoceptor-Mediated Relaxation of Smooth Muscle: Evaluation in Mouse and Guinea-Pig Trachea and Rat Aorta. Biol Pharm Bull. 2020;43(3):493-502. [Content Brief]
- [3]. Stojnova K, et, al. Study on the Complex Equilibria of Molybdenum(VI) with 3,5-Dinitrocatechol and Ditetrazolium Salt. Acta Chim Slov. 2016;63(3):654-60. [Content Brief]
