Prednisolone hemisuccinate (Standard)
Prednisolone hemisuccinate (Standard) (Prednisolone 21-hemisuccinate (Standard)) is the analytical standard of Prednisolone hemisuccinate (HY-B1087). This product is intended for research and analytical applications. Prednisolone hemisuccinate (Prednisolone 21-hemisuccinate) is a prodrug of Prednisolone (HY-17463) and a glucocorticoid. Prednisolone hemisuccinate converts to Prednisolone in vivo. Prednisolone hemisuccinate induces the inactivation of glyceraldehyde-3-phosphate dehydrogenase (GAP-DH) in vitro. Prednisolone hemisuccinate can be used in research related to cataracts.
For research use only. We do not sell to patients.
- CAS No.: 2920-86-7
- Formula: C₂₅H₃₂O₈
- Molecular Weight:460.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 2920-86-7
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Molecular Weight 460.52
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Formula C₂₅H₃₂O₈
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SMILES
C[C@@]12[C@](C(COC(CCC(O)=O)=O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O
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Synonyms
Prednisolone 21-hemisuccinate (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hook DW, et al. Inactivation of glyceraldehyde 3-phosphate dehydrogenase by sugars, prednisolone-21-hemisuccinate, cyanate and other small molecules. Biochim Biophys Acta. 1997;1362(2-3):232-242. [Content Brief]
[2]. Derendorf H, et al. Pharmacokinetics of prednisolone after high doses of prednisolone hemisuccinate. Biopharm Drug Dispos. 1985;6(4):423-432. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)