Prednisolone hemisuccinate (Synonyms: Prednisolone 21-hemisuccinate)

Cat. No.: HY-B1087 Purity: 99.34%: FAQs
Data Sheet SDS COA Handling Instructions

Prednisolone hemisuccinate is a synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions.

For research use only. We do not sell to patients.

Prednisolone hemisuccinate Chemical Structure

CAS No. : 2920-86-7

Size	Price	Stock	Quantity
Solution
10 mM * 1 mL in DMSO	USD 77	In-stock	Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL ready for reconstitution	USD 77	In-stock	Estimated Time of Arrival: December 31
Solid
50 mg	USD 70	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 180	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of Prednisolone hemisuccinate:

Prednisolone In-stock
Prednisolone disodium phosphate In-stock
Prednisolone acetate In-stock

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Description

Prednisolone hemisuccinate is a synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions.

Molecular Weight

460.52

Appearance

Solid

Formula

C₂₅H₃₂O₈

CAS No.

2920-86-7

SMILES

C[[email protected]@]12[[email protected]](C(COC(CCC(O)=O)=O)=O)(O)CC[[email protected]@]1([H])[[email protected]]3([H])CCC4=CC(C=C[[email protected]]4(C)[[email protected]@]3([H])[[email protected]@H](O)C2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (542.86 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1715 mL	10.8573 mL	21.7146 mL
5 mM	0.4343 mL	2.1715 mL	4.3429 mL
10 mM	0.2171 mL	1.0857 mL	2.1715 mL

*Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% saline
Solubility: ≥ 2.08 mg/mL (4.52 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.08 mg/mL (4.52 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO 90% corn oil
Solubility: ≥ 2.08 mg/mL (4.52 mM); Clear solution

*All of the co-solvents are available by MCE.

Purity & Documentation

Purity: 99.34%

Select Batch:

Data Sheet (246 KB) SDS (418 KB)

COA (249 KB) LCMS (269 KB)

Handling Instructions (2659 KB)

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords:

Prednisolone hemisuccinate2920-86-7Prednisolone 21-hemisuccinateGlucocorticoid ReceptorInhibitorinhibitorinhibit

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