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Cat. No.: HY-112573A

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Azapentacene sodium

Name: Azapentacene sodium
Brand: MedChemExpress
SKU: HY-112573A
Availability: PreOrder

(Synonyms: Phacolysine sodium)

Azapentacene (Phacolysine) sodium is an anti-cataract compound. Azapentacene sodium prevents cataract formation in guinea pigs with vitamin C deficiency and delays the progression of congenital cataract in Nakano mice. Azapentacene sodium undergoes reversible one-electron oxidation to form a stable radical cation, undergoes irreversible secondary oxidation to form a hydrolyzable unstable dication, and can also be oxidized by thallium (III) trifluoroacetate in trifluoroacetic acid to generate a detectable radical cation. Azapentacene sodium is used in research related to cataracts, vitamin C deficiency-induced cataracts, and congenital cataracts.

For research use only. We do not sell to patients.

CAS No.: 3863-80-7
Formula: C₁₈H₁₀N₄Na₂O₆S₂
Molecular Weight:488.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Azapentacene sodium Chemical Structure

CAS No.: 3863-80-7

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Biological Activity
- Description
- In Vivo
Chemical Information
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Biological Activity

Description

In Vivo

Azapentacene sodium prevents cataract formation in vitamin C-deficient guinea pigs^[1].
Azapentacene sodium delays the onset of congenital cataracts in Nakano mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3863-80-7
Molecular Weight 488.40
Formula C₁₈H₁₀N₄Na₂O₆S₂
SMILES

O=S(C1=CC(N=C2C=C3C(C=C2N4)=NC5=C(C=CC(S(=O)(O[Na])=O)=C5)N3)=C4C=C1)(O[Na])=O
Synonyms

Phacolysine sodium
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shaver PS. Non-surgical treatment of cataracts (Doctoral dissertation, Pacific University).

[2]. Marti C, et al. Synthesis, properties, and x-ray structure of 6-aza-5, 7, 12, 14-tetrathiapentacene as a novel polyheterocyclic electron donor, and related compounds. The Journal of Organic Chemistry. 1994 Oct;59(21):6200-7.

[3]. Zhao K, et al. Imide-Fused Diazatetracenes: Synthesis, Characterization, and Application in Perovskite Solar Cells. Chemistry. 2020;26(19):4220-4225.

[4]. Jahng Y, Karim M. Synthesis of 5-azapentacene by Friedländer reaction and its properties. Tetrahedron. 2016 Jan 7;72(1):199-204.

[5]. Ji L, et al. Preparation, Properties, and Structures of the Radical Anions and Dianions of Azapentacenes. J Am Chem Soc. 2017;139(44):15968-15976.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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