Potassium guaiacolsulfonate hemihydrate

Name: Potassium guaiacolsulfonate hemihydrate
Brand: MedChemExpress
SKU: HY-107798
Rating: 4.5 (1 reviews)

製品番号: HY-107798 純度: 99.83%: FAQs
Data Sheet SDS COA 取扱説明書

Molarity Calculator

Potassium guaiacolsulfonate hemihydrate is an orally active expectorant used for acute respiratory tract infections. Potassium guaiacolsulfonate hemihydrate helps loosen mucus and used for a cough caused by the common cold, infections or allergies in combination with other agents.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Potassium guaiacolsulfonate hemihydrate 構造式

CAS 番号 : 78247-49-1

容量	価格（税別）	在庫状況	数量
5 mg	USD 25	在庫あり	Estimated Time of Arrival: December 31
10 mg	USD 38	在庫あり	Estimated Time of Arrival: December 31
25 mg	USD 70	在庫あり	Estimated Time of Arrival: December 31
50 mg	USD 100	在庫あり	Estimated Time of Arrival: December 31
100 mg	USD 140	在庫あり	Estimated Time of Arrival: December 31
200 mg		お問い合わせ
500 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

おすすめ

•関連スクリーニングライブラリ:

•関連小分子:

•関連タンパク質:

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

体外実験

Potassium guaiacolsulfonate hemihydrate works by thinning mucus (phlegm) in the lungs and making it less sticky and easier to cough up^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

251.31

分子式

C₇H₈O₅S.1/2H₂O.K

CAS 番号

78247-49-1

Appearance

Solid

Color

White to off-white

SMILES

COC1=CC(S(=O)(O[K])=O)=CC=C1O.COC2=C(C=CC=C2O)S(=O)(O[K])=O.[H]O[H]

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶剤 & 溶解度

体外:

H₂O : 62.5 mg/mL (248.70 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.9791 mL	19.8957 mL	39.7915 mL
5 mM	0.7958 mL	3.9791 mL	7.9583 mL
10 mM	0.3979 mL	1.9896 mL	3.9791 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

体内:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (397.91 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 99.83%

Select Batch:

データシート (277 KB) SDS (252 KB)

COA (255 KB) HNMR (262 KB) LCMS (94 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Thi Huong Hoa Le, et al. Development and Validation of an HPLC Method for Simultaneous Assay of Potassium Guaiacolsulfonate and Sodium Benzoate in Pediatric Oral Powder. J Anal Methods Chem. 2019 Mar 7;2019:6143061. [Content Brief]

[2]. Ozlem Aksu Dönmez, et al. Simultaneous Determination of Potassium Guaiacolsulfonate, Guaifenesin, Diphenhydramine HCl and Carbetapentane Citrate in Syrups by Using HPLC-DAD Coupled With Partial Least Squares Multivariate Calibration. Talanta. 2011 Feb 15;83(5):1601-5. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.9791 mL	19.8957 mL	39.7915 mL	99.4787 mL
	5 mM	0.7958 mL	3.9791 mL	7.9583 mL	19.8957 mL
	10 mM	0.3979 mL	1.9896 mL	3.9791 mL	9.9479 mL
	15 mM	0.2653 mL	1.3264 mL	2.6528 mL	6.6319 mL
	20 mM	0.1990 mL	0.9948 mL	1.9896 mL	4.9739 mL
	25 mM	0.1592 mL	0.7958 mL	1.5917 mL	3.9791 mL
	30 mM	0.1326 mL	0.6632 mL	1.3264 mL	3.3160 mL
	40 mM	0.0995 mL	0.4974 mL	0.9948 mL	2.4870 mL
	50 mM	0.0796 mL	0.3979 mL	0.7958 mL	1.9896 mL
	60 mM	0.0663 mL	0.3316 mL	0.6632 mL	1.6580 mL
	80 mM	0.0497 mL	0.2487 mL	0.4974 mL	1.2435 mL
	100 mM	0.0398 mL	0.1990 mL	0.3979 mL	0.9948 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.