1. Metabolic Enzyme/Protease
  2. Prolyl Endopeptidase (PREP)
  3. Prolylisoleucine

Prolylisoleucine (Pro-Ile) is a dipeptide composed of Proline and Isoleucine, as well as a blocker of endopeptidase 24.16.

For research use only. We do not sell to patients.

Prolylisoleucine

Prolylisoleucine Chemical Structure

CAS No. : 51926-51-3

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Description

Prolylisoleucine (Pro-Ile) is a dipeptide composed of Proline and Isoleucine, as well as a blocker of endopeptidase 24.16[1].

Molecular Weight

228.29

Formula

C11H20N2O3

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

CC[C@H](C)[C@@H](C(O)=O)NC([C@H]1NCCC1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 5 mg/mL (21.90 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3804 mL 21.9020 mL 43.8039 mL
5 mM 0.8761 mL 4.3804 mL 8.7608 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.3804 mL 21.9020 mL 43.8039 mL 109.5098 mL
5 mM 0.8761 mL 4.3804 mL 8.7608 mL 21.9020 mL
10 mM 0.4380 mL 2.1902 mL 4.3804 mL 10.9510 mL
15 mM 0.2920 mL 1.4601 mL 2.9203 mL 7.3007 mL
20 mM 0.2190 mL 1.0951 mL 2.1902 mL 5.4755 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Prolylisoleucine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Prolylisoleucine
Cat. No.:
HY-124005
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