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  4. Triethylene glycol

トリエチレングリコール  (Synonyms: Triethylene glycol; PROTAC Linker 25)

製品番号: HY-W017440 純度: 99.56%
COA 取扱説明書 Technical Support

Triethylene glycol (PROTAC Linker 25) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

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Triethylene glycol

トリエチレングリコール 構造式

CAS 番号 : 112-27-6

容量 価格（税別） 在庫状況 数量
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 38 在庫あり
Solution
10 mM * 1 mL in Water USD 38 在庫あり
Liquid
500 g $35 在庫あり
1 kg $56 在庫あり

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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Based on 0 publication(s) in Google Scholar

Other Forms of Triethylene glycol:

トリエチレングリコール 関連抗体

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PROTAC Linkers アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

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製品説明

Triethylene glycol (PROTAC Linker 25) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外実験

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

トリエチレングリコール 関連抗体
分子量

150.17

分子式

C6H14O4
CAS 番号
Appearance

Liquid (Density: 1.124 g/cm3)

Color

Colorless to light yellow

SMILES

OCCOCCOCCO
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

H2O : 100 mg/mL (665.91 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.6591 mL 33.2956 mL 66.5912 mL
5 mM 1.3318 mL 6.6591 mL 13.3182 mL
10 mM 0.6659 mL 3.3296 mL 6.6591 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

体内:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (665.91 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: 99.88%

COA (240 KB) HNMR (117 KB) GC (91 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.6591 mL 33.2956 mL 66.5912 mL 166.4780 mL
5 mM 1.3318 mL 6.6591 mL 13.3182 mL 33.2956 mL
10 mM 0.6659 mL 3.3296 mL 6.6591 mL 16.6478 mL
15 mM 0.4439 mL 2.2197 mL 4.4394 mL 11.0985 mL
20 mM 0.3330 mL 1.6648 mL 3.3296 mL 8.3239 mL
25 mM 0.2664 mL 1.3318 mL 2.6636 mL 6.6591 mL
30 mM 0.2220 mL 1.1099 mL 2.2197 mL 5.5493 mL
40 mM 0.1665 mL 0.8324 mL 1.6648 mL 4.1619 mL
50 mM 0.1332 mL 0.6659 mL 1.3318 mL 3.3296 mL
60 mM 0.1110 mL 0.5549 mL 1.1099 mL 2.7746 mL
80 mM 0.0832 mL 0.4162 mL 0.8324 mL 2.0810 mL
100 mM 0.0666 mL 0.3330 mL 0.6659 mL 1.6648 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Triethylene glycol Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Triethylene glycol112-27-6PROTAC Linker 25PROTAC Linker25PROTAC Linker-25PROTAC LinkersEnvironmental PollutantsEnvironmental ContaminantsInhibitorinhibitorinhibit

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製品名:
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