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  4. Triethylene glycol

Triethylene glycol  (Synonyms: PROTAC Linker 25)

Cat. No.: HY-W017440 Purity: 99.56%
COA
SDS
Handling Instructions Technical Support

Triethylene glycol (PROTAC Linker 25) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

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Triethylene glycol

Triethylene glycol 화학구조

CAS No. : 112-27-6

사이즈 가격 재고 수량
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in Water 해외재고보유
Liquid
500 g 해외재고보유
1 kg 해외재고보유

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of Triethylene glycol:

Triethylene glycol Related Antibodies

Top Publications Citing Use of Products

View All PROTAC Linkers Isoform Specific Products:

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Triethylene glycol (PROTAC Linker 25) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Triethylene glycol Related Antibodies
분자량

150.17

화학식

C6H14O4
CAS No.
Appearance

Liquid (Density: 1.124 g/cm3)

Color

Colorless to light yellow

SMILES

OCCOCCOCCO
선적

Room temperature in continental US; may vary elsewhere.
보관
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

H2O : 100 mg/mL (665.91 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.6591 mL 33.2956 mL 66.5912 mL
5 mM 1.3318 mL 6.6591 mL 13.3182 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (665.91 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서

Purity: 99.88%

SDS (393 KB)

COA (240 KB) HNMR (117 KB) GC (91 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.6591 mL 33.2956 mL 66.5912 mL 166.4780 mL
5 mM 1.3318 mL 6.6591 mL 13.3182 mL 33.2956 mL
10 mM 0.6659 mL 3.3296 mL 6.6591 mL 16.6478 mL
15 mM 0.4439 mL 2.2197 mL 4.4394 mL 11.0985 mL
20 mM 0.3330 mL 1.6648 mL 3.3296 mL 8.3239 mL
25 mM 0.2664 mL 1.3318 mL 2.6636 mL 6.6591 mL
30 mM 0.2220 mL 1.1099 mL 2.2197 mL 5.5493 mL
40 mM 0.1665 mL 0.8324 mL 1.6648 mL 4.1619 mL
50 mM 0.1332 mL 0.6659 mL 1.3318 mL 3.3296 mL
60 mM 0.1110 mL 0.5549 mL 1.1099 mL 2.7746 mL
80 mM 0.0832 mL 0.4162 mL 0.8324 mL 2.0810 mL
100 mM 0.0666 mL 0.3330 mL 0.6659 mL 1.6648 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Triethylene glycol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Triethylene glycol112-27-6PROTAC Linker 25PROTAC Linker25PROTAC Linker-25PROTAC LinkersEnvironmental PollutantsEnvironmental ContaminantsInhibitorinhibitorinhibit

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상품명:
Triethylene glycol
Cat. No.:
HY-W017440
수량:
MCE Japan Authorized Agent:

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SAFETY DATA SHEET (SDS)

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