(±)-Methotrexate (Synonyms: (±)-Amethopterin; (±)-CL14377; (±)-WR19039)

Cat. No.: HY-121151: Data Sheet
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(±)-Methotrexate ((±)-Amethopterin) is a racemate of Methotrexate (HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of Folic acid into Tetrahydrofolate, and inhibiting DNA synthesis.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

(±)-Methotrexate 화학구조

CAS No. : 60388-53-6

사이즈		재고
MOQ		Minimum order quantity
50 mg		견적 받기
100 mg		견적 받기
250 mg		견적 받기
Other size		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

Other Forms of (±)-Methotrexate:

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고객리뷰

제품 설명	(±)-Methotrexate ((±)-Amethopterin) is a racemate of Methotrexate (HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of Folic acid into Tetrahydrofolate, and inhibiting DNA synthesis^[1].
분자량	454.44
화학식	C₂₀H₂₂N₈O₅
CAS No.	60388-53-6
SMILES	O=C(C(CCC(O)=O)NC(C1=CC=C(C=C1)N(C)CC2=NC3=C(N=C(N=C3N=C2)N)N)=O)O
선적	Room temperature in continental US; may vary elsewhere.
보관	Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서	Data Sheet (264 KB) SDS (252 KB) Handling Instructions (2659 KB)
References	[1]. Tian H, et al. Understanding the mechanisms of action of methotrexate: implications for the treatment of rheumatoid arthritis. Bull NYU Hosp Jt Dis. 2007;65(3):168-73. [Content Brief]

(±)-Methotrexate Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(±)-Methotrexate60388-53-6(±)-Amethopterin (±)-CL14377 (±)-WR19039AntifolateAntimetabolite antifolate dihydrofolate reductasefolic acidtetrahydrofolateDNA synthesisInhibitorinhibitorinhibit

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(±)-Methotrexate (Synonyms: (±)-Amethopterin; (±)-CL14377; (±)-WR19039)

Other Forms of (±)-Methotrexate:

(±)-Methotrexate Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

순도&문서

References

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(±)-Methotrexate Related Classifications

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