Animal-Free LIX/CXCL5 Protein, Mouse (His)

LIX/CXCL5 Protein potentially recruits inflammatory cells to injured or infected tissue, indicating a role in the immune response. Both GCP-2(1-78) and the more potent GCP-2(9-78) variants attract and activate neutrophils. Structurally, the protein can exist as a monomer and form homodimers, showcasing versatility and potential molecular interactions. LIX/CXCL5's ability to attract and activate neutrophils emphasizes its significance in orchestrating immune responses and cellular processes associated with inflammation. Animal-Free LIX/CXCL5 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeLIX/CXCL5 protein, expressed by E. coli, with N-His labeled tag. The total length of Animal-Free LIX/CXCL5 Protein, Mouse (His) is 74 a.a., with molecular weight of ~8.92 kDa.

The LIX/CXCL5 protein is implicated in potentially participating in the recruitment of inflammatory cells to injured or infected tissue, suggesting its role in the immune response. Both GCP-2(1-78) and the more potent GCP-2(9-78) variants of this protein play a role in attracting neutrophils and are involved in the activation of these immune cells. Structurally, the protein exists as a monomer and can also form homodimers, underscoring its versatility and potential for molecular interactions. The ability of LIX/CXCL5 to attract and activate neutrophils highlights its significance in orchestrating immune responses and cellular processes associated with inflammation.

Measure by its ability to chemoattract BaF3 cells transfected with human CXCR2. The ED₅₀ for this effect is <100 ng/mL

Mouse

E. coli

N-His

P50228 (V45-A118)

20311  [NCBI]

VIAATELRCVCLTVTPKINPKLIANLEVIPAGPQCPTVEVIAKLKNQKEVCLDPEAPVIKKIIQKILGSDKKKA

Approximately 8.92 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a solution containing 1X PBS, pH 7.4.

<0.1 EU per 1 μg of the protein by the LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.