Cxcl5 - chemokine (C-X-C motif) ligand 5 Gene

Also Known as LIX; Cxcl6; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20311

Summary

This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils and to have homeostatic and inflammatory functions. In mouse, deficiency of this gene is associated with increased lung inflammation that is neutrophil-dependent. [provided by RefSeq, May 2013]

Cxcl5 Products (1)

mRNA Protein Name
NM_009141.3 NP_033167.2 C-X-C motif chemokine 5 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within leukocyte homeostasis IMP
IMP: Inferred from mutant phenotype
20643340 MGI
acts upstream of or within regulation of chemokine production IMP
IMP: Inferred from mutant phenotype
20643340 MGI
acts upstream of or within regulation of neutrophil mediated killing of gram-negative bacterium IMP
IMP: Inferred from mutant phenotype
20643340 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
20643340 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-X-C motif chemokine 5

  • cytokine LIX

  • granulocyte chemotactic protein-2

  • small inducible cytokine B subfamily, member 5

  • small inducible cytokine subfamily B, member 15

  • small-inducible cytokine B5

Recombinant Cxcl5 Proteins

Cat. No. Product Name Accession Purity
HY-P7383 LIX/CXCL5 Protein, Mouse (74a.a, CHO) P50228 (V45-A118) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P72791 LIX/CXCL5 Protein, Mouse P50228 (A41-Q132) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700173AF Animal-Free LIX/CXCL5 Protein, Mouse (His) P50228 (V45-A118) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-120501 B022 Inhibitor 99.27% Unkown
HY-163475 CXCL-CXCR1/2-IN-1 Inhibitor 99.64% Unkown
HY-149393 RIPK3-IN-3 Inhibitor 95.98% Unkown
HY-176851 GSK1362 Inhibitor 96.38% Unkown
HY-RS03393 CXCL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16639 Cxcl5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24115 Cxcl6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99149 Anti-Mouse TNFR2 Antibody (TR75-54.7) Inhibitor 98.864% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cxcl5 NCBI NCBI:6374