2. Recombinant Proteins
  3. Receptor Proteins
  4. Pattern Recognition Receptors
  5. C-type Lectin Receptors
  6. MDL-1/CLEC5A
  7. CLEC5A/MDL-1 Protein, Rhesus Macaque (HEK293, Fc)

CLEC5A/MDL-1 Protein, Rhesus Macaque (HEK293, Fc)

Cat. No.: HY-P77338
Instrucciones de manejo Technical Support

CLEC5A Protein is a cell surface receptor that signals via TYROBP, and functions as a positive regulator of osteoclastogenesis. CLEC5A Protein regulates inflammatory responses. CLEC5A/MDL-1 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived CLEC5A/MDL-1 protein, expressed by HEK293 , with N-mFc labeled tag.

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  • Descripciòn

Descripciòn

CLEC5A Protein is a cell surface receptor that signals via TYROBP, and functions as a positive regulator of osteoclastogenesis. CLEC5A Protein regulates inflammatory responses. CLEC5A/MDL-1 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived CLEC5A/MDL-1 protein, expressed by HEK293 , with N-mFc labeled tag.
Background

CLEC5A Protein is a critical macrophage receptor for dengue virus serotypes 1-4. The binding of CLEC5A Protein to dengue virus triggers signaling through the phosphorylation of TYROBP, and not results in viral entry, but stimulates pro-inflammatory cytokine release[1][2][3].
Species

Rhesus Macaque
Source

HEK293
Tag

N-mFc
Accession

XP_001085243 (P28-K188)
Gene ID
Molecular Construction
N-term
mFc
CLEC5A (P28-K188)
Accession # XP_001085243
C-term
Protein Length

Partial
Synonyms
C-type lectin domain family 5 member A; MDL-1; CLECSF5
Predicted Molecular Mass
45.3 kDa
Pureza

≥ 90%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentación
Instrucciones de manejo (2659 KB)

CLEC5A/MDL-1 Protein, Rhesus Macaque (HEK293, Fc) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CLEC5A/MDL-1 Protein, Rhesus Macaque (HEK293, Fc)
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