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IL-18R alpha Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P703778
Handling Instructions Technical Support

IL-18R alpha Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-18R alpha protein, expressed by HEK293, with C-His tag.

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100 μg   견적 받기  

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제품 설명

IL-18R alpha Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-18R alpha protein, expressed by HEK293, with C-His tag.
Background

IL-18R alpha is a component of the IL-18 receptor complex, responsible for binding the pro-inflammatory cytokine IL-18 but not IL-1A or IL-1B. It is involved in IL-18-mediated IFNG synthesis from T-helper 1 (Th1) cells and contributes to IL-18-induced cytokine production, either independently of SLC12A3 or as a complex with SLC12A3.
Species

Cynomolgus
Source

HEK293
Tag

C-8*His
Accession

A0A2K5V3J9 (C22-G329)
Protein Length

Extracellular Domain
Synonyms
Interleukin-18 receptor 1; IL-18R1; CDw218a; IL1RRP; IL-18R-alpha; CD218a
AA Sequence

CTSRPHITVVEGEPFYLKYCSCSPAHEIETITKSWYKSSGSQERVELNPRSSSRIALHGCVLEFWPVELNDTGSYSFQMENYTQKWKLNVIRRNKHRCFTERQVTSKTVEVKKFLQITCENSYYQTLVNSTSLYKNCKKLLENNKNPTIKKNAELEDRGYYSCVHFLHHNGKLFNITKTFNITIVEDHSNIVPVLLGPKLNHVAVELGKDVRLNCSALLNEEDVVYWMFGEENGSDPNIHEEKEIRIMTSEGKWHASRVLRIENIGENNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTRG

Predicted Molecular Mass
36.5 kDa
분자량

Approximately 60-70 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Purity

≥ 95%, as determined by Bis-Tris PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
각종 서류
Handling Instructions (2659 KB)

IL-18R alpha Protein, Cynomolgus (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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IL-18R alpha Protein, Cynomolgus (HEK293, His)
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HY-P703778
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