INPP1 Protein, Human (HEK293, His)

INPP1 protein, also known as inositol polyphosphate-1-phosphatase, is a phosphatase that plays a crucial role in inositol phosphate metabolism. The activity of this protein depends on magnesium ions and is responsible for catalyzing the hydrolysis of the phosphate group at position 1 of inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate. INPP1 Protein, Human (HEK293, His) is the recombinant human-derived INPP1 protein, expressed by HEK293 , with C-6*His labeled tag.

INPP1 protein, also known as inositol polyphosphate-1-phosphatase, is a phosphatase enzyme that plays a crucial role in the metabolism of inositol phosphate. This protein is dependent on magnesium ions for its activity and is responsible for catalyzing the hydrolysis of the phosphate group at the 1-position of inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate. This enzymatic activity is essential for regulating the levels of these inositol phosphate molecules within the cell. By removing the phosphate group, INPP1 protein helps to maintain the balance of inositol phosphate signaling pathways, which are involved in various cellular processes such as intracellular signaling, membrane trafficking, and vesicle fusion. The precise role of INPP1 protein in these processes and its impact on cellular function warrant further investigation.

Human

HEK293

C-6*His

P49441 (M1-T399)

3628  [NCBI]

Full Length

MSDILRELLCVSEKAANIARACRQQEALFQLLIEEKKEGEKNKKFAVDFKTLADVLVQEVIKQNMENKFPGLEKNIFGEESNEFTNDWGEKITLRLCSTEEETAELLSKVLNGNKVASEALARVVHQDVAFTDPTLDSTEINVPQDILGIWVDPIDSTYQYIKGSADIKSNQGIFPCGLQCVTILIGVYDIQTGVPLMGVINQPFVSRDPNTLRWKGQCYWGLSYMGTNMHSLQLTISRRNGSETHTGNTGSEAAFSPSFSAVISTSEKETIKAALSRVCGDRIFGAAGAGYKSLCVVQGLVDIYIFSEDTTFKWDSCAAHAILRAMGGGIVDLKECLERNPETGLDLPQLVYHVENEGAAGVDRWANKGGLIAYRSRKRLETFLSLLVQNLAPAETHT

Approximately 40-50 kDa,based on SDS-PAGE under reducing conditions.

≥ 95%, as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.