Nectin-1 Protein, Rat (HEK293, Fc)

Nectin-1 Protein, with carbohydrate and virion binding activities, plays pivotal roles in axon guidance, synapse assembly, and viral entry. Located in dendrites, growth cone membranes, and synapses, Nectin-1 is implicated in human conditions like cleft lip and ectodermal dysplasia. Its biased expression, especially in Kidney (RPKM 45.4) and Brain (RPKM 31.3), underscores its significance in diverse physiological contexts. Nectin-1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Nectin-1 protein, expressed by HEK293 , with C-hFc labeled tag.

Nectin-1 Protein, characterized by its carbohydrate binding and virion binding activities, plays pivotal roles in axon guidance, regulation of synapse assembly, and viral entry into host cells. Distributed across various cellular components, including dendrites, growth cone membranes, and synapses, Nectin-1 is implicated in human conditions such as cleft lip, cleft lip-palate-ectodermal dysplasia syndrome, cleft palate, and ectodermal dysplasia. The biased expression pattern, notably in the Kidney (RPKM 45.4), Brain (RPKM 31.3), and nine other tissues, underscores its significance in diverse physiological contexts.

Rat

HEK293

C-hFc

F1LNP8/NP_001093946 (Q31-A354)

192183  [NCBI]

Partial

QVVQVNDSMYGFIGTDVILHCSFANPLPTVKITQVTWQKASNGSKQNMAIYNPTMGVSVLPPYEKRVEFLRPSFIDGTIRLSHLELEDEGMYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRARKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHRQSLACIVNYHLDRFRESLTLNVQYEPEVTIEGFDGNWYLQRTDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFRGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPTPEHGRRAGQMPTA

Approximately 88-98 kDa,based on SDS-PAGE under reducing conditions.

≥ 90%, as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.