Nectin-1 Protein, Rat (HEK293, Fc)

Nectin-1 Protein, with carbohydrate and virion binding activities, plays pivotal roles in axon guidance, synapse assembly, and viral entry. Located in dendrites, growth cone membranes, and synapses, Nectin-1 is implicated in human conditions like cleft lip and ectodermal dysplasia. Its biased expression, especially in Kidney (RPKM 45.4) and Brain (RPKM 31.3), underscores its significance in diverse physiological contexts. Nectin-1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Nectin-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Nectin-1 Protein, Rat (HEK293, Fc) is 354 a.a., with molecular weight of 88-98 kDa.

Nectin-1 Protein, characterized by its carbohydrate binding and virion binding activities, plays pivotal roles in axon guidance, regulation of synapse assembly, and viral entry into host cells. Distributed across various cellular components, including dendrites, growth cone membranes, and synapses, Nectin-1 is implicated in human conditions such as cleft lip, cleft lip-palate-ectodermal dysplasia syndrome, cleft palate, and ectodermal dysplasia. The biased expression pattern, notably in the Kidney (RPKM 45.4), Brain (RPKM 31.3), and nine other tissues, underscores its significance in diverse physiological contexts.

Rat

HEK293

C-hFc

NP_001093946 (M1-A354)

192183  [NCBI]

88-98 kDa

Greater than 90% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.