Nectin1 - nectin cell adhesion molecule 1 Gene

Also Known as HveC; Pvrl1; nectin-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 192183

Summary

Enables carbohydrate binding activity and virion binding activity. Involved in axon guidance; regulation of synapse assembly; and viral entry into host cell. Located in several cellular components, including dendrite; growth cone membrane; and synapse. Human ortholog(s) of this gene implicated in cleft lip; cleft lip-palate-ectodermal dysplasia syndrome; cleft palate; and ectodermal dysplasia. Orthologous to human NECTIN1 (nectin cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Nectin1 Products (1)

mRNA Protein Name
NM_001100476.1 NP_001093946.1 nectin-1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables carbohydrate binding IDA
IDA: Inferred from direct assay
18181141 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
18181141 RGD
enables protein-containing complex binding IMP
IMP: Inferred from mutant phenotype
15328010 RGD
enables virion binding IMP
IMP: Inferred from mutant phenotype
12584355 RGD
Biological Process GO Annotation Evidence References Source
involved in axon guidance IMP
IMP: Inferred from mutant phenotype
15328010 RGD
involved in regulation of synapse assembly IMP
IMP: Inferred from mutant phenotype
11827984 RGD
involved in regulation of synapse organization EXP
EXP: Inferred from Experiment
11827984 RGD
involved in regulation of synapse organization IDA
IDA: Inferred from direct assay
11827984 RGD
involved in symbiont entry into host cell IMP
IMP: Inferred from mutant phenotype
12584355 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
16801389 RGD
located in dendrite IDA
IDA: Inferred from direct assay
16801389 RGD
located in growth cone membrane IDA
IDA: Inferred from direct assay
18181141 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nectin-1

  • nectin)

  • poliovirus receptor-related 1 (herpesvirus entry mediator C

  • poliovirus receptor-related 1 (herpesvirus entry mediator C

  • nectin)

  • poliovirus receptor-related protein 1

Recombinant Nectin1 Proteins

Cat. No. Product Name Accession Purity
HY-P77470 Nectin-1 Protein, Rat (HEK293, Fc) F1LNP8/NP_001093946 (Q31-A354) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P77471 Nectin-1 Protein, Rat (HEK293, His) F1LNP8/NP_001093946 (Q31-A354) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09174 NECTIN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20215 Nectin1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26721 Nectin1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nectin1 NCBI NCBI:5818