2. Apoptosis
  3. RIP kinase
  4. RIP2 kinase inhibitor 1

RIP2 kinase inhibitor 1 (compound 11) is a potent and selective receptor interacting protein 2 (RIP2) kinase inhibitor with an IC50 of 0.03 μM for RIP2 FP. RIP2 kinase inhibitor 1 is used for autoinflammatory disorders.

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RIP2 kinase inhibitor 1

RIP2 kinase inhibitor 1 Chemische Struktur

CAS. Nr. : 2380028-10-2

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RIP2 kinase inhibitor 1 Related Antibodies

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Beschreibung

RIP2 kinase inhibitor 1 (compound 11) is a potent and selective receptor interacting protein 2 (RIP2) kinase inhibitor with an IC50 of 0.03 μM for RIP2 FP. RIP2 kinase inhibitor 1 is used for autoinflammatory disorders[1].

IC50 & Target

IC50: 0.03 μM (RIP2)[1]
In Vitro

RIP2 kinase inhibitor 1 (compound 11) inhibits human whole blood (hWB; IC50=0.05 μM), activin receptor-like kinase 5 (ALK5; IC50>10 μM), VEGFR2 (IC50=7.94 μM), lymphocyte-specific protein tyrosine kinase (LCK; IC50=31.6 μM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

RIP2 kinase inhibitor 1 Related Antibodies
Molekulargewicht

355.41

Formel

C17H17N5O2S
CAS. Nr.
SMILES

O[C@@H]1[C@H](C2)NC3=C(C(N)=O)C(C4=CC(N=CS5)=C5C=C4)=NN3C[C@H]2C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
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RIP2 kinase inhibitor 1 Related Classifications

  • Molaritätsrechner

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Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RIP2 kinase inhibitor 12380028-10-2RIP kinaseReceptor-interacting protein kinasesRIPKreceptorinteractingproteinRIP2autoinflammatoryInhibitorinhibitorinhibit

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