(S)-BINAP 

(S)-BINAP is the S-isomer of BINAP (HY-Y0003). BINAP is a chiral bisphosphine ligand. (S)-BINAP can be used to assist in the synthesis of compounds with anticancer activity^[1][2][3].

622.67

C₄₄H₃₂P₂

76189-56-5

Solid

White to off-white

C1(C=CC=C2)=C2[C@@]([C@@]3=C(C=CC=C4)C4=CC=C3P(C5=CC=CC=C5)C6=CC=CC=C6)=C(P(C7=CC=CC=C7)C8=CC=CC=C8)C=C1

Room temperature in continental US; may vary elsewhere.

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

• [1]. Tunik S P, et al. Reaction of (S)-BINAP with H4Ru4 (CO) 12. The First Example of Face-Bridging BINAP Coordination and 100% Stereoselectivity in Formation of a Chiral Tetranuclear Cluster Framework. Organometallics, 2004, 23(3): 568-579.

  [2]. Li M, et al. Stereoselective Total Synthesis of Formosanol, Tsugacetal, and Methyl β-Conidendral. Org Lett. 2022 Oct 28;24(42):7812-7816.  [Content Brief]

  [3]. Xin Jin, et al. Synthesis and characterization of a high-purity chiral 5,5'-disulfonato-BINAP ligand and its application in asymmetric hydrogenation of β-keto esters. Molecular Catalysis, 2021, 507, 111562.