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127-79-7

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0512
    Sulfamerazine
    4 Publications Verification

    RP2632

    Antibiotic Bacterial α-synuclein Infection Neurological Disease
    Sulfamerazine (RP2632) is a brain-penetrant and orally active sulfonamide antibiotic and α-synuclein inhibitor with human α-synuclein KD of 352 μM. Sulfamerazine inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine can be used for the research of Parkinson’s disease and bacterial infection .
    Sulfamerazine
  • HY-B0512R

    RP2632 (Standard)

    Reference Standards Bacterial Antibiotic Infection
    Sulfamerazine (Standard) is the analytical standard of Sulfamerazine. This product is intended for research and analytical applications. 0
    Sulfamerazine (Standard)
  • HY-B0512S1

    RP2632-13C6

    Isotope-Labeled Compounds Bacterial Antibiotic Infection
    Sulfamerazine- 13C6 (RP2632- 13C6) is 13C labeled Sulfamerazine (HY-B0512). Sulfamerazine (RP-2632) is a sulfonamide antibacterial. Sulfamerazine, the monomethyl derivative of sulfadiazine, is 2-sulfanilamido-4-methylpyrimidine. Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes.
    Sulfamerazine-13C6
  • HY-B0512S

    RP2632-d4

    Isotope-Labeled Compounds Bacterial Infection
    Sulfamerazine-d4 is a deuterium labeled Sulfamerazine. Sulfamerazine, a sulfonamide antibacterial, inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes .
    Sulfamerazine-d4
  • HY-B0512A

    RP2632 sodium

    Antibiotic Bacterial α-synuclein Infection Neurological Disease
    Sulfamerazine (RP2632) sodium is a brain-penetrant and orally active sulfonamide antibiotic and α-synuclein inhibitor with human α-synuclein KD of 352 μM. Sulfamerazine sodium inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine sodium inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine sodium can be used for the research of Parkinson’s disease and bacterial infection .
    Sulfamerazine sodium

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