Sulfamerazine-d4
Based on 1 Customer Validation
Sulfamerazine-d4 is a deuterium labeled Sulfamerazine. Sulfamerazine (RP2632) is a brain-penetrant and orally active sulfonamide antibiotic and α-synuclein inhibitor with human α-synuclein KD of 352 μM. Sulfamerazine inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine can be used for the research of Parkinson’s disease and bacterial infection.
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- Pureté: 99.00%
- CAS No.: 1020719-84-9
- Formule: C11H8D4N4O2S
- Masse moléculaire:268.33
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Activité biologique
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1020719-84-9
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Unlabeled Cas 127-79-7
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Appearance Solid
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Masse moléculaire 268.33
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Formule C11H8D4N4O2S
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Color White to off-white
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SMILES
O=S(C1=C([2H])C([2H])=C(N)C([2H])=C1[2H])(NC2=NC=CC(C)=N2)=O
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Synonyms
RP2632-d4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 100 mg/mL (372.68 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7268 mL | 18.6338 mL | 37.2675 mL | 93.1689 mL |
| 5 mM | 0.7454 mL | 3.7268 mL | 7.4535 mL | 18.6338 mL | |
| 10 mM | 0.3727 mL | 1.8634 mL | 3.7268 mL | 9.3169 mL | |
| 15 mM | 0.2485 mL | 1.2423 mL | 2.4845 mL | 6.2113 mL | |
| 20 mM | 0.1863 mL | 0.9317 mL | 1.8634 mL | 4.6584 mL | |
| 25 mM | 0.1491 mL | 0.7454 mL | 1.4907 mL | 3.7268 mL | |
| 30 mM | 0.1242 mL | 0.6211 mL | 1.2423 mL | 3.1056 mL | |
| 40 mM | 0.0932 mL | 0.4658 mL | 0.9317 mL | 2.3292 mL | |
| 50 mM | 0.0745 mL | 0.3727 mL | 0.7454 mL | 1.8634 mL | |
| 60 mM | 0.0621 mL | 0.3106 mL | 0.6211 mL | 1.5528 mL | |
| 80 mM | 0.0466 mL | 0.2329 mL | 0.4658 mL | 1.1646 mL | |
| 100 mM | 0.0373 mL | 0.1863 mL | 0.3727 mL | 0.9317 mL |
- Sulfamerazine-d4
- 1020719-84-9
- RP2632-d4
- Isotope-Labeled Compounds
- Bacterial
- Parkinson’s disease
- meningococcal meningitis
- yeast Ure2 protein
- transgenic C. elegans
- pneumococcal infections
- gonococcal infections
- α-synuclein
- beta-hemolytic streptococcus infections
- urinary tract infections
- human neuroblastoma SH-SY5Y cells
- Inhibitor
- inhibitor
- inhibit