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1637-75-8

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By Targets:	Endogenous Metabolite (4) Isotope-Labeled Compounds (2) Reference Standards (1)
By Research Areas:	Neurological Disease (1)

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Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113085

3-Hydroxyhippuric acid 1 Publications Verification	Endogenous Metabolite	Neurological Disease
3-Hydroxyhippuric acid is an acylglycine. 3-Hydroxyhippuric acid inhibits kynureninase (K_i=60 μM). The concentration of 3-Hydroxyhippuric acid in autistic experimental groups is higher than that in control groups. 3-Hydroxyhippuric acid is a biomarker for Clostridium and is positively correlated with the content of Clostridium. 3-Hydroxyhippuric acid is one of the major metabolites of catechin-rich and wine polyphenol-rich diets. 3-Hydroxyhippuric acid can be used in the research of neurodegenerative diseases and autism spectrum disorders .

HY-113085R

3-Hydroxyhippuric acid (Standard)	Reference Standards Endogenous Metabolite	Others
3-Hydroxyhippuric acid (Standard) is the analytical standard of 3-Hydroxyhippuric acid. This product is intended for research and analytical applications. 3-Hydroxyhippuric acid is an acyl glycine. 3-Hydroxyhippuric acid inhibits kynureninase (K_i = 60 μM). 3-Hydroxyhippuric acid is found in higher concentrations in autistic group than in the controls. 3-Hydroxyhippuric acid is a marker of Clostridium species, and has a positive correlation with the level of Clostridia. 3-Hydroxyhippuric acid is one of the main metabolites formed from the catechin diet and wine polyphenol diets .

HY-W769723

3-Hydroxyhippuric acid-13C2,15N	Isotope-Labeled Compounds Endogenous Metabolite	Others
3-Hydroxyhippuric acid- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled 3-Hydroxyhippuric acid (HY-113085). 3-Hydroxyhippuric acid is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids.

HY-178381S

3-Hydroxyhippuric acid-d4	Isotope-Labeled Compounds Endogenous Metabolite	Others
3-Hydroxyhippuric acid-d₄ is the deuterium labeled 3-Hydroxyhippuric acid (HY-113085). 3-Hydroxyhippuric acid is an acyl glycine. 3-Hydroxyhippuric acid inhibits kynureninase (Ki = 60 μM). 3-Hydroxyhippuric acid is found in higher concentrations in autistic group than in the controls. 3-Hydroxyhippuric acid is a marker of Clostridium species, and has a positive correlation with the level of Clostridia. 3-Hydroxyhippuric acid is one of the main metabolites formed from the catechin diet and wine polyphenol diets .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113085

3-Hydroxyhippuric acid 1 Publications Verification	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Phenols Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
3-Hydroxyhippuric acid is an acylglycine. 3-Hydroxyhippuric acid inhibits kynureninase (K_i=60 μM). The concentration of 3-Hydroxyhippuric acid in autistic experimental groups is higher than that in control groups. 3-Hydroxyhippuric acid is a biomarker for Clostridium and is positively correlated with the content of Clostridium. 3-Hydroxyhippuric acid is one of the major metabolites of catechin-rich and wine polyphenol-rich diets. 3-Hydroxyhippuric acid can be used in the research of neurodegenerative diseases and autism spectrum disorders .

HY-113085R

3-Hydroxyhippuric acid (Standard)	Structural Classification Monophenols Ketones, Aldehydes, Acids Phenols Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
3-Hydroxyhippuric acid (Standard) is the analytical standard of 3-Hydroxyhippuric acid. This product is intended for research and analytical applications. 3-Hydroxyhippuric acid is an acyl glycine. 3-Hydroxyhippuric acid inhibits kynureninase (K_i = 60 μM). 3-Hydroxyhippuric acid is found in higher concentrations in autistic group than in the controls. 3-Hydroxyhippuric acid is a marker of Clostridium species, and has a positive correlation with the level of Clostridia. 3-Hydroxyhippuric acid is one of the main metabolites formed from the catechin diet and wine polyphenol diets .

Cat. No.	Product Name	Chemical Structure

HY-W769723

3-Hydroxyhippuric acid-13C2,15N
3-Hydroxyhippuric acid- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled 3-Hydroxyhippuric acid (HY-113085). 3-Hydroxyhippuric acid is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids.

HY-178381S

3-Hydroxyhippuric acid-d4
3-Hydroxyhippuric acid-d₄ is the deuterium labeled 3-Hydroxyhippuric acid (HY-113085). 3-Hydroxyhippuric acid is an acyl glycine. 3-Hydroxyhippuric acid inhibits kynureninase (Ki = 60 μM). 3-Hydroxyhippuric acid is found in higher concentrations in autistic group than in the controls. 3-Hydroxyhippuric acid is a marker of Clostridium species, and has a positive correlation with the level of Clostridia. 3-Hydroxyhippuric acid is one of the main metabolites formed from the catechin diet and wine polyphenol diets .

3-Hydroxyhippuric acid-d4

3-Hydroxyhippuric acid-d₄ is the deuterium labeled 3-Hydroxyhippuric acid (HY-113085). 3-Hydroxyhippuric acid is an acyl glycine. 3-Hydroxyhippuric acid inhibits kynureninase (Ki = 60 μM). 3-Hydroxyhippuric acid is found in higher concentrations in autistic group than in the controls. 3-Hydroxyhippuric acid is a marker of Clostridium species, and has a positive correlation with the level of Clostridia. 3-Hydroxyhippuric acid is one of the main metabolites formed from the catechin diet and wine polyphenol diets .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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1637-75-8

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products