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73069-27-9

" in MedChemExpress (MCE) Product Catalog:

2

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2

Natural
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6065
    Praeruptorin A
    3 Publications Verification

    (+)-Praeruptorin A

    Calcium Channel Drug Isomer Cytochrome P450 iGluR Apoptosis Cardiovascular Disease Neurological Disease
    Praeruptorin A ((+)-Praeruptorin A) is an orally active isomer of (±)-Praeruptorin A (HY-N0081). Praeruptorin A also acts as a Calcium channel blocker. Praeruptorin A can be isolated from Peucedanum. Praeruptorin A serves as a substrate for CYP3A4. Praeruptorin A downregulates NMDA receptors containing GluN2B and inhibits neuronal Apoptosis. Praeruptorin A mediates vasodilation, inhibits vascular hypertrophy and reduces blood pressure. Praeruptorin A can be used in research related to neurological diseases, myocardial ischemia, heart failure, exertional angina, renovascular hypertension and spontaneous hypertension .
    Praeruptorin A
  • HY-N6065R

    (+)-Praeruptorin A (Standard)

    Reference Standards NF-κB Inflammation/Immunology
    Praeruptorin A (Standard) is the analytical standard of Praeruptorin A. This product is intended for research and analytical applications. Praeruptorin A is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin A exerts anti-inflammatory effects in vitro through inhibition of NF-κB activation .
    Praeruptorin A (Standard)

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