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Isoforms Recommended: PARP1
Results for "

ARTD-1

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

3

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-19351
    MN-64
    3 Publications Verification

    		 PARP Cancer
    MN-64 is a potent tankyrase 1 inhibitor, with IC50s of 6 nM, 72 nM, 19.1 μM, and 39.4 μM for TNKS1, TNKS2, ARTD1 and ARTD2, respectively.
    MN-64
  • HY-108631
    EB-47 dihydrochloride
    2 Publications Verification

    		 PARP Inflammation/Immunology
    EB-47 dihydrochloride, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM. EB-47 mimics the substrate NAD + and extends from the nicotinamide to the adenosine subsite [1].
    EB-47 dihydrochloride
  • HY-148710
    ARTD10/PARP10-IN-2

    		PARP Inflammation/Immunology
    ARTD10/PARP10-IN-2 (compound 19) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 ARTD1/PARP1 with IC50s of 2.0 μM, and 9.7 μM, respectively [1].
    <em>ARTD</em>10/PARP10-IN-2
  • HY-148709
    ARTD10/PARP10-IN-1

    		PARP Inflammation/Immunology
    ARTD10/PARP10-IN-1 (compound 23) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD7/PARP15, ARTD8/PARP14, ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 (ARTD1/PARP1) with IC50s of 1.7 μM, 1.6 μM, 0.8 μM, and 4.4 μM, respectively [1].
    <em>ARTD</em>10/PARP10-IN-<em>1</em>
  • HY-15046
    EB-47

    		PARP Cardiovascular Disease Inflammation/Immunology
    EB-47, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM. EB-47 mimics the substrate NAD + and extends from the nicotinamide to the adenosine subsite [1].
    EB-47

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