2. Cell Cycle/DNA Damage Epigenetics
  3. PARP
  4. ARTD10/PARP10-IN-2

ARTD10/PARP10-IN-2 (compound 19) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 ARTD1/PARP1 with IC50s of 2.0 μM, and 9.7 μM, respectively.

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ARTD10/PARP10-IN-2 Chemical Structure

ARTD10/PARP10-IN-2 Chemical Structure

CAS No. : 1708103-69-8

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ARTD10/PARP10-IN-2 Related Antibodies

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Description

ARTD10/PARP10-IN-2 (compound 19) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 ARTD1/PARP1 with IC50s of 2.0 μM, and 9.7 μM, respectively[1].

IC50 & Target[1]

ARTD1/PARP1

9.7 μM (IC50)

ARTD10/PARP10

2.0 μM (IC50)

ARTD8/PARP14

>20 μM (IC50)

ARTD7/PARP15

>20 μM (IC50)

Molecular Weight

247.25

Formula

C12H13N3O3
CAS No.
SMILES

CNC(/C=C\C(NC1=CC(C(N)=O)=CC=C1)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ARTD10/PARP10-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ARTD10/PARP10-IN-21708103-69-8PARPpoly ADP ribose polymeraseInhibitorinhibitorinhibit

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