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AZ+2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Deubiquitinase (1) PI3K (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (1) Inflammation/Immunology (1)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-111570

PI3Kγ inhibitor AZ2 2 Publications Verification	PI3K	Inflammation/Immunology
PI3Kγ inhibitor AZ2 is a highly selective PI3Kγ inhibitor (The pIC₅₀ value for PI3Kγ is 9.3). PI3Kγ inhibitor AZ2 can be used for the research of inflammatory and immune diseases .

HY-RS01295

AZI2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
AZI2 Human Pre-designed siRNA Set A contains three designed siRNAs for AZI2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

AZI2 Human Pre-designed siRNA Set A AZI2 Human Pre-designed siRNA Set A

HY-122686

USP25/28-IN-2	Deubiquitinase	Cancer
USP25/28-IN-2 (compound AZ2) is a selectivity dual USP25/USP28 inhibitor with USP28 IC₅₀ values of 0.9 μM, USP28 K_a values of 0.9 μM, and USP25 IC₅₀ values of 0.88 μM. USP25/28-IN-2 modulates USP25 and USP28 activity to affect downstream pathways, modulates c-Myc oncoprotein total levels and half-life, induces apoptosis, reduces cell viability. USP25/28-IN-2 can be used for the research of colorectal carcinoma, colorectal adenocarcinoma .

Host:	Rabbit (2)
Reactivity:	Human (2) Rat (2)
Application:	WB (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (1) Recombinant (1)
Modification:	Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82481

	AZI2 Antibody (YA2226) AZ2; NAP1; TILP	WB	Human, Rat
	AZI2 Antibody (YA2226) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AZI2.

HY-P82481A

	AZI2 Antibody (YA2226)(PBS only) AZ2; NAP1; TILP	WB	Human, Rat
	AZI2 Antibody (YA2226) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AZI2.

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AZI2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
AZI2 Human Pre-designed siRNA Set A contains three designed siRNAs for AZI2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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