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Results for "

Acridone

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W007771
    Acridone

    		Bacterial Infection Cancer
    Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities .
    <em>Acridone</em>
  • HY-34887
    Acridone-4-carboxylic acid

    		Others Others
    Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM .
    <em>Acridone</em>-4-carboxylic acid
  • HY-147182
    3,6-Diamino-9(10H)-acridone

    		Topoisomerase Others
    3,6-Diamino-9(10H)-acridone is a topoisomerase inhibitor .
    3,6-Diamino-9(10H)-<em>acridone</em>
  • HY-N9147
    1-Hydroxy-N-methylacridone

    		Others Neurological Disease
    1-Hydroxy-N-methylacridone is an acridone alkaloid from Boronia lanceolate .
    1-Hydroxy-N-methylacridone
  • HY-128913
    1,3-Dihydroxy-4-methoxy-10-methylacridin-9(10H)-one

    		Bacterial Infection
    1,3-Dihydroxy-4-methoxy-10-methylacridin-9(10H)-one is an acridone alkaloid compound isolated from the fruits of Z. leprieurii and Z. zanthoxyloides. 1,3-Dihydroxy-4-methoxy-10-methylacridin-9(10H)-one has antibacterial activity .
    1,3-Dihydroxy-4-methoxy-10-methylacridin-9(10H)-one
  • HY-110217
    BMS-566419

    		Others Others
    BMS-566419 is an acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase (IMPDH). Inosine monophosphate dehydrogenase (IMPDH) is a key enzyme in the de novo synthesis of guanosine nucleotides. BMS-566419 has clinical utility for the research of transplant rejection .
    BMS-566419
  • HY-138961
    ER-27319

    		Syk Inflammation/Immunology
    ER-27319, an acridone derivative, is a potent and selective SYK inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 μM and can be used for study in allergic diseases .
    ER-27319
  • HY-108489
    ER-27319 maleate

    		Syk Inflammation/Immunology
    ER-27319 (maleate), an acridone derivative, is a potent and selective SKY inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 (maleate) inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 μM and can be used for study in allergic diseases [1] [2] .
    ER-27319 maleate
  • HY-143279
    Topoisomerase II inhibitor 3

    		Topoisomerase Apoptosis Cancer
    Topoisomerase II inhibitor 3 (Compound 6 h ) is a acridone derivatives, as well as a Type II DNA topoisomerase (topo II) inhibitor , as a topo IIα/β inhibitor with the value of IC50 is 0.17 μM for topo IIα and the value of IC50 is 0.23 μM for topo IIβ subtypes, caused obvious DNA damage, and induced apoptosis by triggering the loss of mitochondrial membrane potential .
    Topoisomerase II inhibitor 3
  • HY-143280
    Topoisomerase II inhibitor 4

    		Topoisomerase Cancer
    Topoisomerase II inhibitor 4 (compound E17) is a potent Topoisomerase II inhibitor. Topoisomerase II inhibitor 4 triggers G2/M cell cycle arrest and shows anti-tumor activity with strong cytotoxic and anti-proliferative effect .
    Topoisomerase II inhibitor 4

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