3,6-Diamino-9(10H)-acridone

Cat. No.: HY-147182: Data Sheet Handling Instructions
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3,6-Diamino-9(10H)-acridone is a topoisomerase inhibitor.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

3,6-Diamino-9(10H)-acridone 화학구조

CAS No. : 42832-87-1

사이즈	재고	수량
50 mg	견적 받기 5 - 7 weeks 4-6 weeks 6 - 8 weeks 2-3 weeks	Estimated Time of Arrival: December 31
100 mg	견적 받기 5 - 7 weeks 4-6 weeks 6 - 8 weeks 2-3 weeks	Estimated Time of Arrival: December 31
250 mg	견적 받기 5 - 7 weeks 4-6 weeks 6 - 8 weeks 2-3 weeks	Estimated Time of Arrival: December 31
500 mg	견적 받기
1 g	견적 받기

Synthetic products have potential research and development risk.

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* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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Topoisomerase Topo I Topo II DNA gyrase

Biological Activity
순도&문서
References
고객리뷰

제품 설명

3,6-Diamino-9(10H)-acridone is a topoisomerase inhibitor^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A2780	IC₅₀	37 μM Compound: 22	Cytotoxic potency required to inhibit A2780 cell growth by 50% after cell drug contact for 96 hrs Cytotoxic potency required to inhibit A2780 cell growth by 50% after cell drug contact for 96 hrs	[PMID: 9371240]
CH1	IC₅₀	>100 μM Compound: 22	Cytotoxic potency required to inhibit CH1 cell growth by 50% Cytotoxic potency required to inhibit CH1 cell growth by 50%	[PMID: 9371240]
L1210	IC₅₀	35 μM Compound: 22	Cytotoxic potency required to inhibit L1210 cell growth by 50% after cell drug contact for 48 hrs Cytotoxic potency required to inhibit L1210 cell growth by 50% after cell drug contact for 48 hrs	[PMID: 9371240]
SK-OV-3	IC₅₀	>100 μM Compound: 22	Cytotoxic potency required to inhibit SKOV-3 cell growth 50% Cytotoxic potency required to inhibit SKOV-3 cell growth 50%	[PMID: 9371240]

분자량

225.25

화학식

C₁₃H₁₁N₃O

CAS No.

42832-87-1

SMILES

O=C1C2=C(C=C(N)C=C2)NC3=CC(N)=CC=C13

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Nunhart P, et al. Fluorinated 3,6,9-trisubstituted acridine derivatives as DNA interacting agents and topoisomerase inhibitors with A549 antiproliferative activity. Bioorg Chem. 2020 Jan;94:103393. [Content Brief]