Acridone-4-carboxylic acid

Cat. No.: HY-34887 Purity: 98.69%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC₅₀ of 43 μM.

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Acridone-4-carboxylic acid Chemical Structure

CAS No. : 24782-64-7

Size	Price	Stock	Quantity
5 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 160	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

239.23

Formula

C₁₄H₉NO₃

CAS No.

24782-64-7

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C(C=CC=C1C2=O)=C1NC3=C2C=CC=C3)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (418.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.1801 mL	20.9004 mL	41.8008 mL
5 mM	0.8360 mL	4.1801 mL	8.3602 mL
10 mM	0.4180 mL	2.0900 mL	4.1801 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.69%

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Data Sheet (274 KB) SDS (393 KB)

COA (254 KB) HNMR (355 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. Pal C, et al. Synthesis of novel heme-interacting acridone derivatives to prevent free heme-mediated protein oxidation and degradation. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3563-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.1801 mL	20.9004 mL	41.8008 mL	104.5019 mL
	5 mM	0.8360 mL	4.1801 mL	8.3602 mL	20.9004 mL
	10 mM	0.4180 mL	2.0900 mL	4.1801 mL	10.4502 mL
	15 mM	0.2787 mL	1.3934 mL	2.7867 mL	6.9668 mL
	20 mM	0.2090 mL	1.0450 mL	2.0900 mL	5.2251 mL
	25 mM	0.1672 mL	0.8360 mL	1.6720 mL	4.1801 mL
	30 mM	0.1393 mL	0.6967 mL	1.3934 mL	3.4834 mL
	40 mM	0.1045 mL	0.5225 mL	1.0450 mL	2.6125 mL
	50 mM	0.0836 mL	0.4180 mL	0.8360 mL	2.0900 mL
	60 mM	0.0697 mL	0.3483 mL	0.6967 mL	1.7417 mL
	80 mM	0.0523 mL	0.2613 mL	0.5225 mL	1.3063 mL
	100 mM	0.0418 mL	0.2090 mL	0.4180 mL	1.0450 mL