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Results for "

D10 P. falciparum

" in MedChemExpress (MCE) Product Catalog:
Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-W020111
    7-Chloro-4-(piperazin-1-yl)quinoline

    		Sirtuin Parasite Infection
    7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1.18 μM and 0.97 μM, respectively .
    7-Chloro-4-(piperazin-1-yl)quinoline
  • HY-181864
    Rac1-IN-6

    		Parasite Infection
    Rac1-IN-6 (Compound 5e) is a selective Rac1 inhibitor and antimalarial agent. Rac1-IN-6 inhibits Rac1 activation induced by the Escherichia coli CNF1 toxin. Rac1-IN-6 suppresses the growth of chloroquine-sensitive Plasmodium falciparum D10 (IC50 = 76.0 nM) and chloroquine-resistant Plasmodium falciparum W2 (IC50 = 236.6 nM) .
    Rac1-IN-6

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