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Results for "

H7

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

3

Peptides

2

Inhibitory Antibodies

1

Natural
Products

34

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99284

    MK-0646; H7C10

    IGF-1R Apoptosis Cancer
    Dalotuzumab (MK-0646) is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R. Dalotuzumab acts by inhibiting IGF-1- and IGF-2-mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo .
    Dalotuzumab
  • HY-100983

    PKC Cancer
    Protein kinase inhibitor H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor. At 100 μM, Protein kinase inhibitor H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) .
    Protein kinase inhibitor <em>H-7</em> dihydrochloride
  • HY-131900

    PKC Cancer
    Protein kinase inhibitor H-7 is a potent inhibitor of protein kinase C (PKC) and cyclic nucleotide dependent protein kinase, with a Ki of 6 μM for PKC .
    Protein kinase inhibitor <em>H-7</em>
  • HY-142523

    Fluorescent Dye Cancer
    H7 is a second near-infrared (NIR-II) fluorophore .
    <em>H7</em>
  • HY-P5675

    Bacterial Infection
    Bombinin H7 is an antimicrobial peptide derived from skin secretions of Bombina. Bombinin H7 is active against Bacillus megaterium Bm11 with a lethal concentration of 25.2 μM .
    Bombinin <em>H7</em>
  • HY-RS15995

    Small Interfering RNA (siRNA) Others

    ZC3H7B Human Pre-designed siRNA Set A contains three designed siRNAs for ZC3H7B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ZC3H7B Human Pre-designed siRNA Set A
    ZC3H7B Human Pre-designed siRNA Set A
  • HY-P1602

    Bacterial Infection
    Apidaecin IB is a insect antimicrobial peptide, with minimum inhibitory concentration (MIC) values of 8 μM for E. coli (ML35, O18K1H7 and ATCC 25922).
    Apidaecin IB
  • HY-153932

    PROTACs p38 MAPK Cancer
    NR-7h is a potent and selective p38α and p38β degrader with DC50 values of 24 nM and 27.2 nM for p38α in T47D, MB-MDA-231 cells, respectively .
    NR-<em>7</em>h
  • HY-11009
    CGP60474
    5 Publications Verification

    CDK PKC Cancer
    CGP60474, a highly potent anti-endotoxemic agent, is a potent cyclin-dependent kinase (CDK) inhibitor (IC50 values are 26, 3, 4, 216, 10, 200 and 13 nM for CDK1/B, CDK2/E, CDK2/A, CDK4/D, CDK5/p25, CDK7/H and CDK9/T, respectively). CGP60474 is a selective and ATP-competitive PKC inhibitor .
    CGP60474
  • HY-100858

    Influenza Virus Infection
    PP7 is a potent PB1-PB2 interaction inhibitor with an IC50 of 8.6 μM, and their inhibition against viral polymerase activity (IC50=9.5 μM). PP7 shows antiviral activities against influenza A virus (IAV), including A(H1N1)pdm09 (EC50=1.4 μM), A(H7N9) and A(H9N2) subtypes .
    PP<em>7</em>

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