1. Anti-infection
  2. Influenza Virus
  3. PP7

PP7 

Cat. No.: HY-100858
Handling Instructions

PP7 is a potent PB1-PB2 interaction inhibitor with an IC50 of 8.6 μM, and their inhibition against viral polymerase activity (IC50=9.5 μM). PP7 shows antiviral activities against influenza A virus (IAV), including A(H1N1)pdm09 (EC50=1.4 μM), A(H7N9) and A(H9N2) subtypes.

For research use only. We do not sell to patients.

PP7 Chemical Structure

PP7 Chemical Structure

CAS No. : 433238-84-7

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Description

PP7 is a potent PB1-PB2 interaction inhibitor with an IC50 of 8.6 μM, and their inhibition against viral polymerase activity (IC50=9.5 μM). PP7 shows antiviral activities against influenza A virus (IAV), including A(H1N1)pdm09 (EC50=1.4 μM), A(H7N9) and A(H9N2) subtypes[1].

IC50 & Target

IC50: 8.6 μM (PB1-PB2 interaction)[1]

Molecular Weight

377.22

Formula

C₁₈H₁₄Cl₂N₂O₃

CAS No.

433238-84-7

SMILES

ClC1=CC=C(N2C(/C(C(N2)=O)=C/C3=CC=C(OCC)C=C3)=O)C=C1Cl

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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