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Results for "

Imidazopyridine

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108341A
    PF-06424439 methanesulfonate
    20+ Cited Publications

    		 Acyltransferase Metabolic Disease
    PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM . PF-06424439 methanesulfonate is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate .
    PF-06424439 methanesulfonate
  • HY-108341
    PF-06424439
    20+ Cited Publications

    		 Acyltransferase Metabolic Disease
    PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM . PF-06424439 is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate .
    PF-06424439
  • HY-17421
    Tenatoprazole

    TU-199

    		 Proton Pump Infection Inflammation/Immunology
    Tenatoprazole (TU-199) is an orally active imidazopyridine-based proton pump inhibitor with a prolonged plasma half-life. Tenatoprazole inhibits hog gastric H +/K +-ATPase activity with an IC50 of 6.2 μM. Tenatoprazole blocks the interaction of ubiquitin with the ESCRT-1 factor Tsg101, inhibits production of several enveloped viruses, including EBV .
    Tenatoprazole
  • HY-108278
    Zolimidine

    		Drug Derivative Endocrinology
    Zolimidine, a derivate of imidazopyridine, is an orally active antiulcer agent. Zolimidine stimulates mucus secretion in intestinal mucosal cells and enhacnes intestinal wall more resistant to ulceration. Zolimidine exhibits gastroprotective effect in duodenal ulcer research .
    Zolimidine
  • HY-111351
    MLK-IN-1

    		Mixed Lineage Kinase Neurological Disease
    MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor, compound 68, extracted from patent US20140256733A1 .
    MLK-IN-1
  • HY-15961
    Antitumor agent-3

    		Drug Derivative Cancer
    Antitumor agent-3 is a potent compound which comprises a new imidazopyridine having excellent antitumor activity as an active ingredient.
    Antitumor agent-3
  • HY-179209
    TLR9-IN-2

    		Toll-like Receptor (TLR) Inflammation/Immunology
    TLR9-IN-2 (Compound 20) is a selective inhibitor of Toll-like receptor 9 (TLR9) with IC50 values for TLR9, TLR7, and TLR8 of 25, 1400, and > 50,000 nM respectively. TLR9-IN-2 can be used for the study of fibrosis, autoimmune and inflammatory diseases .
    TLR9-IN-2
  • HY-103030
    PI3K-IN-32

    		PI3K Cancer
    PI3K-IN-32 is an imidazopyridine derivative with a 3-NH2 substituent, and also a PI3K p110α inhibitor. PI3K-IN-32 is applicable for cancer research .
    PI3K-IN-32
  • HY-149998
    Antimycobacterial agent-5

    		Bacterial Reactive Oxygen Species (ROS) Apoptosis Infection
    Antimycobacterial agent-5 (compound 27) is an imidazopyridine amide targeting mycobacterial electron transport chain (ETC) airway CIII2CIV2 supercomplexes. The IC50 value of Antimycobacterial agent-5 against Mycobacterium smegmatisCIII2CIV2 is 441 nM .
    Antimycobacterial agent-5
  • HY-17421R
    Tenatoprazole (Standard)

    TU-199 (Standard)

    		 Proton Pump Reference Standards Infection Inflammation/Immunology
    Tenatoprazole (Standard) is the analytical standard of Tenatoprazole. This product is intended for research and analytical applications. Tenatoprazole (TU-199) is an orally active imidazopyridine-based proton pump inhibitor with a prolonged plasma half-life. Tenatoprazole inhibits hog gastric H+/K+-ATPase activity with an IC50 of 6.2 μM. Tenatoprazole blocks the interaction of ubiquitin with the ESCRT-1 factor Tsg101, inhibits production of several enveloped viruses, including EBV .
    Tenatoprazole (Standard)
  • HY-147851
    BACE1-IN-12

    		Beta-secretase Neurological Disease
    BACE1-IN-12 (compound 7g) is a potent and BBB-penetrated BACE1 inhibitor, with an IC50 of 8.9 µM. BACE1-IN-12 shows selective BuChE (butyrylcholinesterase) inhibitory activity with an IC50 of 3.2 µM. BACE1-IN-12 shows effective antioxidant effect with an IC50 of 10.2 μM (DPPH). BACE1-IN-12 might be served as a potential anti-Alzheimer agent .
    BACE1-IN-12
  • HY-183528
    Anticoccidial agent-1

    		Parasite Infection
    Anticoccidial agent-1 is an imidazopyridine anticoccidial agent with an IC50 of 0.044. Anticoccidial agent-1 can be used for the research of coccidiosis .
    Anticoccidial agent-1
  • HY-183574
    Antimalarial agent 62

    		Parasite Infection
    Antimalarial agent 62 is an orally active imidazopyridine-6-carboxamide antimalarial agent with a high resistance barrier. Antimalarial agent 62 kills trophozoite-stage Plasmodium ring forms, effectively clears dihydroartemisinin-induced dormant Plasmodium ring forms, and eliminates parasitemia in mice infected with Plasmodium yoelii. In AReBaR resistance omics screening, Antimalarial agent 62 is not affected by different target- and efflux-mediated resistance mutations and can withstand resistance selection. Antimalarial agent 62 has been applied to studies of malaria-related mechanisms .
    Antimalarial agent 62
  • HY-108278R
    Zolimidine (Standard)

    		Drug Derivative Reference Standards Endocrinology
    Zolimidine (Standard) is the analytical standard of Zolimidine (HY-108278). This product is intended for research and analytical applications. Zolimidine, a derivate of imidazopyridine, is an orally active antiulcer agent. Zolimidine stimulates mucus secretion in intestinal mucosal cells and enhacnes intestinal wall more resistant to ulceration. Zolimidine exhibits gastroprotective effect in duodenal ulcer research .
    Zolimidine (Standard)
  • HY-108341R
    PF-06424439 (Standard)

    		Reference Standards Acyltransferase Metabolic Disease
    PF-06424439 (Standard) is the analytical standard of PF-06424439 (HY-108341). This product is intended for research and analytical applications. PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM . PF-06424439 is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate .
    PF-06424439 (Standard)
  • HY-108341AR
    PF-06424439 methanesulfonate (Standard)

    		Reference Standards Acyltransferase Metabolic Disease
    PF-06424439 methanesulfonate (Standard) is the analytical standard of PF-06424439 (methanesulfonate) (HY-108341A). This product is intended for research and analytical applications. PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM . PF-06424439 methanesulfonate is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate .
    PF-06424439 methanesulfonate (Standard)

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