5 Results for "

L-02 hepatocytes

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "L-02 hepatocytes" in MCE Product Catalog:

Cat. No.: HY-N6066
CAS No.: 78478-28-1
Praeruptorin E is an orally active pyranocoumarin compound. Praeruptorin E can be isolated from the dried roots of Peucedanum praeruptorum Dunn. Praeruptorin E reduces the expression of NF-κB. Praeruptorin E upregulates the expression of PXR and CYP3A4. Praeruptorin E inhibits Th2 cytokines, TNF-α, IL6, MPO, and blocks the Ca 2+ slow channel. Praeruptorin E promotes pulmonary tissue repair and relaxes porcine coronary artery strips. Praeruptorin E protects mice from lipopolysaccharide- and hydrochloric acid-induced acute lung injury. Praeruptorin E can be used in studies related to asthma and acute lung injury .
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Cat. No.: HY-N4124
CAS No.: 137551-39-4
Poricoic acid B is a triterpenoid compound that can be isolated from Poria cocos. Poricoic acid B inhibits intracellular lipid accumulation and reduces the levels of hepatocyte injury markers. Poricoic acid B inhibits the production of NO, TNF-α, IL-1β and IL-6, thereby exerting anti-inflammatory activity. Poricoic acid B can be used in the research of metabolic dysfunction-associated fatty liver disease and inflammatory diseases [3].
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Cat. No.: HY-N16513
CAS No.: 105181-07-5
Muurol-4-ene-3,8-dione (Compound 2), a sesquiterpene, is one of the main hepatotoxic components in Eupatorium adenophorum. Muurol-4-ene-3,8-dione has an inhibitory effect on the growth of both the normal human hepatocyte cell L02 and the human hepatocellular carcinoma cell HepG2 with IC50 values of 87.52 and 104.48 μM .
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Cat. No.: HY-138958
CAS No.: 192880-96-9
Research Areas:  

Infection

HT1171 is a potent and selective inhibitor of mycobacterium tuberculosis proteasome. HT1171 shows strong anti-tuberculosis activity against Mycobacterium tuberculosis H37Rv with an MIC90 of 2 μg/mL and an MIC of 4 μg/mL. When HT1171 concentration is 100 μM, the inhibition rate of human normal hepatocytes L02 is 53.8%. HT1171 can be used in the research of antitubercular agent .
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Cat. No.: HY-183716
CAS No.: 2489184-70-3
Target:  

Drug Derivative

Research Areas:  

Cancer

Mito-TP-2 is a triptolide (HY-32735) derivative. Mito-TP-2 exhibits concentration-dependent cytotoxicity in cancer cells. Mito-TP-2 is selectively driven and accumulated into the mitochondria of tumor cells by mitochondrial transmembrane potential and exerts specific mitochondrial toxicity. Mito-TP-2 can be used for the research of liver cancer, breast cancer, and non-small cell lung cancer .
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