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Results for "

MERS-CoV 3CLpro

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-149535
    Iscartrelvir

    WU-04

    		 SARS-CoV Infection
    Iscartrelvir (WU-04) is a non-covalent inhibitor of SARS-CoV-2, targeting the 3CLpro protein. Iscartrelvir has high inhibitory effect on the 3CLpro protein of 6 SARS-CoV-2 variants (Alpha, Beta, Gamma, Delta, Lambda and Omicron) and 2 coronaviruses (SARS-CoV and MERS-CoV) .
    Iscartrelvir
  • HY-162674
    MERS-CoV-IN-2

    		SARS-CoV Infection
    MERS-CoV-IN-2 (compound 3c) is a MERS-CoV 3CLpro inhibitor (IC50=17nM). MERS-CoV-IN-2 inhibits the activity of the 3CLpro enzyme by binding to the active site of the enzyme, specifically the S4 subsite, thereby exhibiting antiviral activity against SARS-CoV-2 and MERS-CoV .
    MERS-CoV-IN-2
  • HY-184269
    SARS-CoV-2 3CLpro-IN-38

    		SARS-CoV Virus Protease Cathepsin Infection
    SARS-CoV-2 3CLpro-IN-38 is a 3CLpro inhibitor with an IC50 of 0.34 μM against SARS-CoV-2 3CLpro and an IC50 of 0.12 μM against MERS-CoV 3CLpro. SARS-CoV-2 3CLpro-IN-38 inhibits recombinant Cathepsin L with an IC50 of 5.23 nM. SARS-CoV-2 3CLpro-IN-38 inhibits cysteine proteases essential for the replication of SARS-CoV-2 and MERS-CoV, suppresses host cysteine proteases involved in coronavirus entry, blocks viral entry, and inhibits viral replication. SARS-CoV-2 3CLpro-IN-38 can be used in the research of COVID-19 .
    SARS-CoV-2 3CLpro-IN-38
  • HY-183956
    GC813

    		SARS-CoV Infection
    GC813 is a MERS-CoV 3CL protease (3CLpro) and MERS-CoV main protease (Mpro) inhibitor. GC813 can be used for the research of middle east respiratory syndrome .
    GC813

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